CAJ | 학술논문

目的探讨大连汉族正常人皮肤摩擦系数是否与性别和年龄有关.方法 414名汉族志愿者参加本项研究,年龄2个月至79岁,男187例,女227例;平均年龄(35.80±1.33)岁.根据生长发育期将其分为3组:0～12岁为青春期前组;20～40岁为青壮年组;60～80岁为老年组.利用Courage-Khazaka多功能皮肤生理仪Frictiometer(R) FR 770 and Corneometer(R) CM 825探头分别测量不同部位皮肤摩擦系数和角质层的含水量(电容).结果在男性,除老年组前额部位皮肤摩擦系数明显低于手背部位外(P＜0.05),在其他各年龄组中,各部位之间皮肤摩擦系数差异无统计学意义;而在女性,除青壮年组前额部位的皮肤摩擦系数明显低于手背和眼外眦部位外(P＜0.001),在其他各年龄组中,各部位之间皮肤摩擦系数差异也无统计学意义.在男性,同一部位各年龄组之间皮肤摩擦系数差异无统计学意义;然而在女性的前额部位,老年的皮肤摩擦系数明显大于青春期前和青壮年(P值均＜0.01);在女性的眼外眦和手背部位,青壮年的皮肤摩擦系数明显大于青春期前和老年(P值均＜0.01).除青壮年女性手背和眼外眦部位的皮肤摩擦系数明显大于男性外(P分别＜0.05和0.001),在其他各年龄组和各部位中,男女间皮肤摩擦系数差异无统计学意义.在青壮年男性,各部位皮肤摩擦系数与角质层的含水量呈正相关性(前额r=0.6342,P＜0.0001;眼外眦r=0.4501,P＜0.001;手背r=0.3627,P＜0.01);而在女性,仅老年前额和眼外眦的皮肤摩擦系数与角质层含水量呈正相关性(前额r=0.2797,P＜0.05;眼外眦r=0.486,P＜0.001).结论汉族正常人皮肤摩擦系数与性别、年龄、部位及角质层含水量有关.
목적 탐토대련한족정상인피부마찰계수시부여성별화년령유관.방법 414명한족지원자삼가본항연구,년령2개월지79세,남187례,녀227례;평균년령(35.80±1.33)세.근거생장발육기장기분위3조:0～12세위청춘기전조;20～40세위청장년조;60～80세위노년조.이용Courage-Khazaka다공능피부생리의Frictiometer(R) FR 770 and Corneometer(R) CM 825탐두분별측량불동부위피부마찰계수화각질층적함수량(전용).결과 재남성,제노년조전액부위피부마찰계수명현저우수배부위외(P＜0.05),재기타각년령조중,각부위지간피부마찰계수차이무통계학의의;이재녀성,제청장년조전액부위적피부마찰계수명현저우수배화안외자부위외(P＜0.001),재기타각년령조중,각부위지간피부마찰계수차이야무통계학의의.재남성,동일부위각년령조지간피부마찰계수차이무통계학의의;연이재녀성적전액부위,노년적피부마찰계수명현대우청춘기전화청장년(P치균＜0.01);재녀성적안외자화수배부위,청장년적피부마찰계수명현대우청춘기전화노년(P치균＜0.01).제청장년녀성수배화안외자부위적피부마찰계수명현대우남성외(P분별＜0.05화0.001),재기타각년령조화각부위중,남녀간피부마찰계수차이무통계학의의.재청장년남성,각부위피부마찰계수여각질층적함수량정정상관성(전액r=0.6342,P＜0.0001;안외자r=0.4501,P＜0.001;수배r=0.3627,P＜0.01);이재녀성,부노년전액화안외자적피부마찰계수여각질층함수량정정상관성(전액r=0.2797,P＜0.05;안외자r=0.486,P＜0.001).결론 한족정상인피부마찰계수여성별、년령、부위급각질층함수량유관.
Objective To determine whether skin friction coefficient (SFC) is associated with gender and age in a normal Chinese Han population. Methods A total of 414 Chinese Han subjects including 187males and 227 females, who were aged from 0.15 to 79 years (mean age: 35.80 ± 1.33 years), were enrolled in this study. According to human development stages, subjects were divided into pre-puberty group (aged 0 - 12years), young group (aged 20 - 40 years) and old group (aged 60 - 80 years). SFC and stratum corneum capacitance were measured with A Frictiometer(R) FR 770 and Corneometer(R) CM 825 (C&K MPA 5), respectively,on the dorsal hand, forehead, as well as canthus. Results SFC was higher on the dorsal hand than on the forehead in old males (P ＜ 0.05 ), and higher on the dorsal hand and canthus than on the forehead in young females (both P ＜ 0.001 ), while no significant difference was observed between the three measured sites in other groups of females or males (all P ＞ 0.05 ). In males, SFC on each measured site was similar among the three groups. In contrast, SFC was significantly higher on the forehead of females in aged than in young and pre-puberty groups (both P ＜ 0.01 ), and on the canthus and dorsal hand of females in young than in pre-puberty and aged groups (all P ＜ 0.01 ). The SFC on the canthus and dorsal hands of young females was higher than that of age-matched males (P ＜ 0.0001 and 0.05, respectively). A positive correlation was found between SFC and stratum corneum hydration in young males (foreahead: r = 0.6342, P ＜ 0.0001; canthus: r = 0.4501, P ＜0.001; dorsal hands: r = 0.3627, P ＜ 0.01 ). Moreover, SFC on the forehead (r = 0.2797, P ＜ 0.05) and canthus (r = 0.486, P ＜ 0.001 ) was also positively correlated with stratum corneum hydration in old females.Conclusion Skin friction coefficient varies with age, gender, body sites and stratum comeum hydration in normal Han populations.