CAJ | 학술논문

背景:电针及氯米帕明并用治疗强迫症是中西医结合的行为尝试.目的:探讨针药并用治疗强迫症的长期疗效及对社会功能恢复的影响.设计:以患者为研究对象的观察对比研究.地点:一所市级精神卫生中心的病房.对象:本研究在淄博市第五人民医院完成.选择1997-01/2003-10本院的住院患者30例,年龄18～57岁,平均(33±12)岁.将30例患者随机分为两组,试验组15例,男8例,女7例.对照组15例,男7例,女8例.方法:试验组用电针内关、人中、承浆合并氯米帕明口服,对照组单用氯米帕明.于治疗前、治疗后4,6,8周末、6个月随访分别用强迫量表(Y-Bocs)、副反应量表(TESS)和临床评定标准评定疗效及副反应,治疗后8周用社会功能缺陷筛选量表(SDSS)评定.主要观察指标:Y-BOCS,TESS,SDSS量表评分结果比较.结果:治疗4,6,8周末Y-Bocs分减分率试验组高于对照组,但两组差异无显著性意义(P＞0.05).TESS分对照组明显高于试验组(P＜0.01),SDSS"职业和工作"因子分试验组低于对照组(P＜0.05).结论:应用电针内关、人中、承浆治疗强迫症状,减少了氯米帕明的副反应,能够改善强迫症患者的生活质量.
배경:전침급록미파명병용치료강박증시중서의결합적행위상시.목적:탐토침약병용치료강박증적장기료효급대사회공능회복적영향.설계:이환자위연구대상적관찰대비연구.지점:일소시급정신위생중심적병방.대상:본연구재치박시제오인민의원완성.선택1997-01/2003-10본원적주원환자30례,년령18～57세,평균(33±12)세.장30례환자수궤분위량조,시험조15례,남8례,녀7례.대조조15례,남7례,녀8례.방법:시험조용전침내관、인중、승장합병록미파명구복,대조조단용록미파명.우치료전、치료후4,6,8주말、6개월수방분별용강박량표(Y-Bocs)、부반응량표(TESS)화림상평정표준평정료효급부반응,치료후8주용사회공능결함사선량표(SDSS)평정.주요관찰지표:Y-BOCS,TESS,SDSS량표평분결과비교.결과:치료4,6,8주말Y-Bocs분감분솔시험조고우대조조,단량조차이무현저성의의(P＞0.05).TESS분대조조명현고우시험조(P＜0.01),SDSS"직업화공작"인자분시험조저우대조조(P＜0.05).결론:응용전침내관、인중、승장치료강박증상,감소료록미파명적부반응,능구개선강박증환자적생활질량.
BACKGROUND: The combination of electric acupuncture and clomipramine is the behavior attempt in the integration of Chinese and western medicine in the treatment of obsession.OBJECTIVE: To probe into the long-term therapeutic effects of the combination of acupuncture and medication on obsession and its influence on social functional recovery.DESIGN: Controlled study with observation in which the patients were taken as the objects.SETTING: Wards of a municipal mental hygiene center PARTICIPANTS: The research was performed in the Fifth People's Hospital of Zibo. Totally 30 inpatients were selected from January 1997 to October 2003 in the hospital, aged varied from 18 to 57 years, at the average of (33 ± 12) years. Thirty patients were divided randomly into two groups,named as experimental group, 15 cases with 8 males and 7 females; and the control group, 15 cases with 7 males and 8 females.METHODS: In the experimental group, electric acupuncture was applied on neiguan, renzhong and chengjiang, together with clomipramine orally. In the control group, only clomipramine was applied. The therapeutic effects and side effects were evaluated with Y-Bocs, TESS and clinical evaluation standards successively before the treatment, at the 4th, 6th and 8th weekends after treatment and by 6 months following visits. SDSS evaluation was carried on at the 8th week of the treatment.MAIN OUTCOME MEASURES: Comparisons of evaluating results with Y-Bocs, TESS and SDSS.RESULTS: At the 4th, 6th and 8th weekends of the treatment, the score-reducing rates of Y-Bocs in the experimental group were higher than those in the control group, but the difference was not significant ( P ＞ 0.05). The scores of TESSin the control group were remarkably higher than those in the experimental group( P ＜ 0. 01 ) . Factor scores of "profession and work" in SDSS in the experimental group were lower than that in the control group ( P ＜ 0.05 ).CONCLUSION: Electric acupuncture on neiguan, renzhong and chengjiang reduces the side effect of clomipramine in the treatment of obsession and improve the living quality of the patients with obsession.