CAJ | 학술논문

本文构建了一个Delaunay模型对电压门控钾离子(Kv)通道进行预测.该方法通过建立一系列带有隐含变量的单纯形来分类电压门控钾离子通道,然后通过未知序列在主成分空间里面的投影来预测结构.结果表明该模型无论是在分类和结构预测上均可以得到很好的结果.
본문구건료일개Delaunay모형대전압문공갑리자(Kv)통도진행예측.해방법통과건립일계렬대유은함변량적단순형래분류전압문공갑리자통도,연후통과미지서렬재주성분공간리면적투영래예측결구.결과표명해모형무론시재분류화결구예측상균가이득도흔호적결과.
A Delaunay model to predict voltage-gated potassium (Kv) channels was developed, in which a series of simplexes with latent variables were constructed to classify the families of Kv channels and then each query sequence was projected to principle component space (PC-space) to predict their topology. The results suggested that this method can perform reasonably well in both classification and structure recognition. It is anticipated that this method can be as a complementary tool for experiments to provide structural information of a novel Kv channels and be helpful to other algorithms for structure prediction.