CAJ | 학술논문

目的了解本地区泌尿生殖道解脲脲原体(Uu)和人型支原体(Mh)的感染状况及药物敏感性,指导临床医生合理应用抗生素.方法应用法国生物梅里埃公司提供的IST试剂盒进行支原体鉴定及9种药物敏感检测,并对结果进行统计学分析.结果 2 410例门诊患者中检出支原体阳性者共1 401例,总感染率为58.1%,其中Uu单独感染901例(占37.4%),Mh感染85例(占3.5%),Uu+Mh混合感染415例(占17.2%).交沙霉素和原始霉素敏感率最高,对Uu感染分别是98.8%和98.8%,对Uu+Mh混合感染分别为86.9%和86.8%;环丙沙星敏感率最低,分别是6.4%和2.6%.结论支原体感染以Uu为主,交沙霉素和原始霉素敏感率最高,环丙沙星敏感率最低.临床应选用培养敏感的抗菌药物,提高治疗效果.
목적 료해본지구비뇨생식도해뇨뇨원체(Uu)화인형지원체(Mh)적감염상황급약물민감성,지도림상의생합리응용항생소.방법 응용법국생물매리애공사제공적IST시제합진행지원체감정급9충약물민감검측,병대결과진행통계학분석.결과 2 410례문진환자중검출지원체양성자공1 401례,총감염솔위58.1%,기중Uu단독감염901례(점37.4%),Mh감염85례(점3.5%),Uu+Mh혼합감염415례(점17.2%).교사매소화원시매소민감솔최고,대Uu감염분별시98.8%화98.8%,대Uu+Mh혼합감염분별위86.9%화86.8%;배병사성민감솔최저,분별시6.4%화2.6%.결론 지원체감염이Uu위주,교사매소화원시매소민감솔최고,배병사성민감솔최저.림상응선용배양민감적항균약물,제고치료효과.
Objective To investigate infection statue and antibiotic susceptibility of Mycoplasma urealyticum and Mycoplasma hominis in the genitourinary tract in our area, so as to instruct the rational use of antibiotics. Methods Genitourinary secretions were collected with swabs. They were cultured with the diagnostic kit of Mycoplasma (Biomerieux Company) to detect M. urealyticum and M. hominis. Meanwhile the susceptibility of Mycoplasma against 9 antimicrobial agents was tested with the same kit. According to the manual of the kit,the results were read. The data were statistically analyzed. Results A total of 2 410 samples were collected, and the positive rate was 58. 1%. Among 1410 positive cases of Mycoplasma, 901 cases were M. urealyticum (37.4%), 85 were M. hominis (3.5%), and 415 were M. urealyticum combined with M. hominis (17.2%).The susceptibility rate of M. urealyticum to josamycin, pristinamycin, ciprofloxacin was 98. 8%, 98. 8% and 6. 4% respectively, while the susceptibility rate of M. urealyticum combined with M. horninis was 86.9%,86. 8% and 2.6% respectively. Conclusion M. urealyticum is the major cause of Mycoplasma infection in genitourinary system. Josamycin and pfistinamycin are more effective than other antimicrobial agents to treat Mycoplasma irffection. Ciprofloxacin is more resistant than other antimicrobial agents. Sensitive antibiotics should be selected based on the results of bacterial culture and drug sensitivity tests so as to raise the clinical curative effects.