CAJ | 학술논문

miRNA系统在高等多细胞真核生物中得到了广泛深入的研究.近年来,人们在单细胞真核生物上的miRNA研究也取得了重要进展.这不仅丰富了人们对miRNA在整个生物界中的认识,更重要的是对于揭示miRNA这一表达调节系统是如何存生物界中起源进化的问题具有重要意义.该文结合作者在最低等单细胞真核生物--贾第虫上的研究结果,对该领域的研究进展作一概述,并对有关miRNA这一系统的起源进化问题进行了探讨.
miRNA계통재고등다세포진핵생물중득도료엄범심입적연구.근년래,인문재단세포진핵생물상적miRNA연구야취득료중요진전.저불부봉부료인문대miRNA재정개생물계중적인식,경중요적시대우게시miRNA저일표체조절계통시여하존생물계중기원진화적문제구유중요의의.해문결합작자재최저등단세포진핵생물--가제충상적연구결과,대해영역적연구진전작일개술,병대유관miRNA저일계통적기원진화문제진행료탐토.
microRNAs (miRNAs) in higher multicellular eukaryotes have been extensively studied in recent years. Great progresses have also been achieved for miRNAs in unicellular eukaryotes. All these studies not only enrich our knowledge about the complex expression regulation system in diverse organisms, but also have evolutionary significance for understanding the origin of this system. In this review, Authors summarize the recent advance in the studies of miRNA in unicellular eukaryotes, including that on the most primitive unicellular eukaryote--Giardia. The origin and evolution of miRNA system is also discussed.