国际外科学杂志
國際外科學雜誌
국제외과학잡지
INTERNATIONAL JOURNAL OF SURGERY
2010年
10期
690-693
,共4页
下肢缺血性疾病%内皮祖细胞%移植%血管新生
下肢缺血性疾病%內皮祖細胞%移植%血管新生
하지결혈성질병%내피조세포%이식%혈관신생
Ischemic disease of lower extremity%Endothelial progenitor cell%Transplantation%Angiogenesis
随着人口老龄化、饮食结构改变及引起血管疾病高危因素的增加,下肢缺血性疾病已成为老年人的多发病,是截肢致残的主要原因.作为21世纪最先进的技术,干细胞移植快速地应用于临床,并被认为可能是根治性治疗下肢缺血性疾病的方法之一,内皮祖细胞由于其独特的生物学特性逐渐成为治疗这一病变的新方向和新研究热点.本文着重介绍内皮祖细胞治疗肢体缺血性病变的理论基础和研究进展.
隨著人口老齡化、飲食結構改變及引起血管疾病高危因素的增加,下肢缺血性疾病已成為老年人的多髮病,是截肢緻殘的主要原因.作為21世紀最先進的技術,榦細胞移植快速地應用于臨床,併被認為可能是根治性治療下肢缺血性疾病的方法之一,內皮祖細胞由于其獨特的生物學特性逐漸成為治療這一病變的新方嚮和新研究熱點.本文著重介紹內皮祖細胞治療肢體缺血性病變的理論基礎和研究進展.
수착인구노령화、음식결구개변급인기혈관질병고위인소적증가,하지결혈성질병이성위노년인적다발병,시절지치잔적주요원인.작위21세기최선진적기술,간세포이식쾌속지응용우림상,병피인위가능시근치성치료하지결혈성질병적방법지일,내피조세포유우기독특적생물학특성축점성위치료저일병변적신방향화신연구열점.본문착중개소내피조세포치료지체결혈성병변적이론기출화연구진전.
With the population aging, diet changing and incveasing risk factors on vascular disease, the lower extremity ischemic disease has become a frequently occurring disease of older person, and it is the main reason for amputation disability. In the 21st century the stem cells transplantation is one of the most advanced technologies and has been applied quickly to clinical therapy, regarded as a radical treatment of lower extremity ischemic disease. Endothelial progenitor cells have gradually become a new direction and a new research focus because of its unique biological characteristics in the treatment of this disease. This article focuses on endothelial progenitor cells in treating extremity ischemia lesions on the theoretical basis and research developments.
