CAJ | 학술논문

目的对进口与国产培美曲塞二钠联合顺铂一线治疗非小细胞肺癌(NSCLC)进行成本效果分析.方法筛选2009年9月至2011年7月我院应用培美曲塞二钠联合顺铂一线治疗NSCLC患者60例,按化疗方案中选用培美曲塞二钠的不同将60例患者分为进口药组(应用进口培美曲塞二钠,32例)和国产药组(应用国产培美曲塞二钠,28例),运用药物经济学成本-效果分析方法进行研究.结果进口药组与国产药组有效率分别为43.7％ (14/32)和32.1％ (9/28),差异有统计学意义(P＜0.05)；成本效果比分别为892.4、724.2,差异无统计学意义(P＞0.05).结论国产培美曲塞二钠更具成本效果性,但与进口培美曲塞二钠相比,疗效尚需提高.
목적 대진구여국산배미곡새이납연합순박일선치료비소세포폐암(NSCLC)진행성본효과분석.방법 사선2009년9월지2011년7월아원응용배미곡새이납연합순박일선치료NSCLC환자60례,안화료방안중선용배미곡새이납적불동장60례환자분위진구약조(응용진구배미곡새이납,32례)화국산약조(응용국산배미곡새이납,28례),운용약물경제학성본-효과분석방법진행연구.결과 진구약조여국산약조유효솔분별위43.7％ (14/32)화32.1％ (9/28),차이유통계학의의(P＜0.05)；성본효과비분별위892.4、724.2,차이무통계학의의(P＞0.05).결론 국산배미곡새이납경구성본효과성,단여진구배미곡새이납상비,료효상수제고.
Objective To analyze the cost effectiveness of abroad and domestic pemetrexed combined with cisplatin as first-line treatment in non-small cell lung cancer (NSCLC).Methods From September 2009 to July 2011,60 patients of NSCLC who were treated with pemetrexed combined with cisplatin as first-line treatment in our hospital were enrolled.Among these patients,32 ones had abroad pemetrexed disodium and 28 ones were domestic pemetrexed disodium.The cost effectiveness analysis of pharmacoeconomics was analyzed.Results The effectiveness of the two groups was 43.7％ (14/32) and 32.1％ (9/28).The ratio of cost effectiveness of the two groups was 892.40 and 724.20 respectively.Conclusion Domestic pemetrexed disodium has cost effectiveness.But compared with abroad pemetrexed disodium,domestic pemetrexed disodium has lower clinical effectiveness.