CAJ | 학술논문

目的探讨甲状旁腺癌(parathyroid carcinoma,PTC)的诊断与外科治疗方法.方法对郑州大学第一附属医院1997年至2010年收治的6例PTC患者的临床表现、实验室检查及手术治疗进行回顾性分析.结果 6例患者血钙及血清甲状旁腺激素(PTH)均高于正常值,术后均发生短时的低血钙症.均行甲状旁腺癌切除术加患侧甲状腺近全切除术.5例术中冷冻明确诊断,1例术后石蜡病理及免疫组织化学确诊.结论术前结合血钙、PTH与超声、CT、99Tcm-MIBI影像学检查有助于定性、定位诊断,手术切除甲状旁腺癌以及同侧甲状腺是一种良好的手术方法.
목적 탐토갑상방선암(parathyroid carcinoma,PTC)적진단여외과치료방법.방법 대정주대학제일부속의원1997년지2010년수치적6례PTC환자적림상표현、실험실검사급수술치료진행회고성분석.결과 6례환자혈개급혈청갑상방선격소(PTH)균고우정상치,술후균발생단시적저혈개증.균행갑상방선암절제술가환측갑상선근전절제술.5례술중냉동명학진단,1례술후석사병리급면역조직화학학진.결론 술전결합혈개、PTH여초성、CT、99Tcm-MIBI영상학검사유조우정성、정위진단,수술절제갑상방선암이급동측갑상선시일충량호적수술방법.
Objective To evaluate the diagnosis and surgical treatment of parathyroid carcinoma (PTC). Methods Six patients with parathyroid carcinoma who were treated in our hospital from 1997 to 2010 were analysed retrospectively. Results Patients showed hypercalcemia and elevated parathyroid hormone(PTH). All patients presented with temporary hypocalcemia after surgery. Parathyroidectomy and ipsilateral near-total thyroidectomy was performed in all patients. Frozen section established diagnosis in 5 patients. Routine histopathology combined with immuohistochemistry established the diagnosis in one patient. Conclusions Blood calcium,blood PTH,ultrasonography,CT and 99 Tcm-MIBI are helpful to diagnosis. The operative removal of parathyroid carcinoma with thyroid at the same side is a better radical treatment.