CAJ | 학술논문

目的探讨腹水超滤浓缩腹腔回输治疗顽固性腹水的疗效及对肾功能的影响.方法 60例顽固性腹水患者在基础治疗前提下应用腹水超滤浓缩腹腔回输治疗,并观察治疗前后腹胀缓解、意识、血压变化及腹腔感染情况,内生肌酐清除率(CCr)、血K+、Na+离子浓度及腹水蛋白的变化.结果腹水超滤浓缩腹腔回输治疗可不同程度缓解腹胀.治疗后无病例出现意识障碍、血压不稳定、腹腔感染;对血K+、Na+离子浓度无明显影响;腹水蛋白在连续3次治疗中为升高,之后1周为降低.CCr>50 ml/min的患者可增加肾小球滤过率,CCr≤50 ml/min的患者反而降低肾小球滤过率.结论腹水超滤浓缩腹腔回输操作简单,疗效确切、不良反应相对少,值得临床推广并进一步摸索.
목적 탐토복수초려농축복강회수치료완고성복수적료효급대신공능적영향.방법 60례완고성복수환자재기출치료전제하응용복수초려농축복강회수치료,병관찰치료전후복창완해、의식、혈압변화급복강감염정황,내생기항청제솔(CCr)、혈K+、Na+리자농도급복수단백적변화.결과 복수초려농축복강회수치료가불동정도완해복창.치료후무병례출현의식장애、혈압불은정、복강감염;대혈K+、Na+리자농도무명현영향;복수단백재련속3차치료중위승고,지후1주위강저.CCr>50 ml/min적환자가증가신소구려과솔,CCr≤50 ml/min적환자반이강저신소구려과솔.결론 복수초려농축복강회수조작간단,료효학절、불량반응상대소,치득림상추엄병진일보모색.
Objective To explore the therapeutic effects of uhrafihration and reinfusion of ascites to treat stubborn aseites and its influence to renal function in clinic. Methods The based treatment was given, 60 patients adopted ultrafihration and reinfusion of ascites to treat stubborn aseites, meanwhile, distention, consciousness, blood pressure,abdominal infection, endogenous creatinine clearance (CCr), concentration of K+ , Na+ and ascites proteins were observed before and after the treatment. Results The treatment could mitigate the distention of the patients in different degrees. After the treatment, the abnormality to consciousness, blood pressure and abdominal infection never happened. There was no significant change in the concentration of K+ , Na+. The concentration of ascites proteins raised within three continuous treatments, but later decreased within one week. When CCr was above 50 ml/min, the treatment raised the glomerular filtration rate; on the contrary,CCr under 60 ml/min, the glomerular filtration rate decreased.Conclusion Ultrafihration and reinfusion of ascites in treating stubborn ascites is a simple-operating, effective method with based treatment. The side effect of this treatment is relatively less. The long-term curative effect would need further study.