CAJ | 학술논문

目的:探讨橙皮苷在碱性有机溶剂辅助下的酸促水解及产物的初步分离,以期通过此法米制备两种水解产物橙皮素-7-葡萄糖苷和橙皮素.方法:对影响水解的主要因素:酸的种类、水解方式、酸浓度、有机溶剂的种类和水解时间进行探讨.结果:水解的较佳条件为:橙皮苷先用氢氧化钠溶液和异丙醇组成的碱性有机溶剂溶解,再在100℃条件下酸水解,盐酸浓度为1.5mol/L,水解时间为15～45min.利用混合产物中3种物质在丙酮及其水溶液中溶解性的差异来分离纯化水解产物也取得了一定的效果.结论:橙皮苷在碱性有机溶剂辅助和一定的盐酸浓度下可以得到较好地水解.
목적:탐토등피감재감성유궤용제보조하적산촉수해급산물적초보분리,이기통과차법미제비량충수해산물등피소-7-포도당감화등피소.방법:대영향수해적주요인소:산적충류、수해방식、산농도、유궤용제적충류화수해시간진행탐토.결과:수해적교가조건위:등피감선용경양화납용액화이병순조성적감성유궤용제용해,재재100℃조건하산수해,염산농도위1.5mol/L,수해시간위15～45min.이용혼합산물중3충물질재병동급기수용액중용해성적차이래분리순화수해산물야취득료일정적효과.결론:등피감재감성유궤용제보조화일정적염산농도하가이득도교호지수해.
To provide a method for preparing two hesperidin hydrolysates,namely hesperetin-7-glucoside and hesperetin,acid catalyzed hydrolysis of hesperidin in an alkaline organic solvent system was explored and the resulting hesperidin hydrolysates were preliminarily separated.Crucial factors affecting acid-catalyzed hydrolysis,such as acid kind,hydrolysis mode,acid concentration,composition of alkaline organic solvent system and hydrolysis time were investigated.Results showed that full dissolution of hesperidin in a mixed system of sodium hydroxide solution and isopropyl alcohol under preheating condition followed by hydrolysis for 15-45 min catalyzed with 1.5 mol/L hydrochloric acid resulted in an optimal hesperidin hydrolysis.Moreover,a satisfying separation of 3 hydrolysis products obtained was achieved using their difference of dissolubility in acetone and water.Thus,some concentration of hydrochloric acid in an appropriate alkaline organic solvent medium can give a good catalysis for hesperidin hydrolysis.