中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2012年
4期
426-429
,共4页
孟凡刚%李强%付莹%赵志军%周令望%王虎%刘辉%李德安%王丽华
孟凡剛%李彊%付瑩%趙誌軍%週令望%王虎%劉輝%李德安%王麗華
맹범강%리강%부형%조지군%주령망%왕호%류휘%리덕안%왕려화
大骨节病%硒%T-2毒素
大骨節病%硒%T-2毒素
대골절병%서%T-2독소
Kaschin-Beck disease%Selenium%T-2 toxin
目的 调查青海省兴海县大骨节病相对活跃病区儿童大骨节病流行现状,以及当地儿童硒营养水平和家庭主食粮食T-2毒素污染水平.方法 2009年对兴海县唐乃亥乡上、中、下3个村7~ 12岁儿童进行右手X线拍片,根据《大骨节病诊断标准》(GB 16003-1995)进行诊断.同时采集拍片儿童的枕部发样、饮水以及主食粮食(小麦和/或面粉),2,3-二氨基萘荧光法测定其头发、饮水和主食粮食硒含量,酶联免疫吸附试验(ELISA法)检测主食粮食T-2毒素污染水平.结果 儿童大骨节病X线总检出率为12.20%(31/254),其中下村X线检出率达到14.97%(22/147),上村X线检出率为9.52%(6/63),中村X线检出率为6.82%(3/44).病区儿童内外环境硒水平普遍较低,头发、饮水、小麦、面粉硒含量分别为(0.250±0.136)mg/kg、(0.16±0.05)μg/L、(0.0045±0.0030)mg/kg、(0.0067±0.0116)mg/kg.病区儿童家庭主食粮食T-2毒素含量较高,小麦为(78.91±46.17)μg/kg;面粉为(47.47±46.47) μg/kg.结论 青海省兴海县大骨节病相对活跃病区7~ 12岁儿童内外环境硒水平较低,而主食粮食T-2毒素污染水平较高,与当地儿童大骨节病病情分布基本一致.
目的 調查青海省興海縣大骨節病相對活躍病區兒童大骨節病流行現狀,以及噹地兒童硒營養水平和傢庭主食糧食T-2毒素汙染水平.方法 2009年對興海縣唐迺亥鄉上、中、下3箇村7~ 12歲兒童進行右手X線拍片,根據《大骨節病診斷標準》(GB 16003-1995)進行診斷.同時採集拍片兒童的枕部髮樣、飲水以及主食糧食(小麥和/或麵粉),2,3-二氨基萘熒光法測定其頭髮、飲水和主食糧食硒含量,酶聯免疫吸附試驗(ELISA法)檢測主食糧食T-2毒素汙染水平.結果 兒童大骨節病X線總檢齣率為12.20%(31/254),其中下村X線檢齣率達到14.97%(22/147),上村X線檢齣率為9.52%(6/63),中村X線檢齣率為6.82%(3/44).病區兒童內外環境硒水平普遍較低,頭髮、飲水、小麥、麵粉硒含量分彆為(0.250±0.136)mg/kg、(0.16±0.05)μg/L、(0.0045±0.0030)mg/kg、(0.0067±0.0116)mg/kg.病區兒童傢庭主食糧食T-2毒素含量較高,小麥為(78.91±46.17)μg/kg;麵粉為(47.47±46.47) μg/kg.結論 青海省興海縣大骨節病相對活躍病區7~ 12歲兒童內外環境硒水平較低,而主食糧食T-2毒素汙染水平較高,與噹地兒童大骨節病病情分佈基本一緻.
목적 조사청해성흥해현대골절병상대활약병구인동대골절병류행현상,이급당지인동서영양수평화가정주식양식T-2독소오염수평.방법 2009년대흥해현당내해향상、중、하3개촌7~ 12세인동진행우수X선박편,근거《대골절병진단표준》(GB 16003-1995)진행진단.동시채집박편인동적침부발양、음수이급주식양식(소맥화/혹면분),2,3-이안기내형광법측정기두발、음수화주식양식서함량,매련면역흡부시험(ELISA법)검측주식양식T-2독소오염수평.결과 인동대골절병X선총검출솔위12.20%(31/254),기중하촌X선검출솔체도14.97%(22/147),상촌X선검출솔위9.52%(6/63),중촌X선검출솔위6.82%(3/44).병구인동내외배경서수평보편교저,두발、음수、소맥、면분서함량분별위(0.250±0.136)mg/kg、(0.16±0.05)μg/L、(0.0045±0.0030)mg/kg、(0.0067±0.0116)mg/kg.병구인동가정주식양식T-2독소함량교고,소맥위(78.91±46.17)μg/kg;면분위(47.47±46.47) μg/kg.결론 청해성흥해현대골절병상대활약병구7~ 12세인동내외배경서수평교저,이주식양식T-2독소오염수평교고,여당지인동대골절병병정분포기본일치.
Objective To investigate the present prevalence state of children's Kaschin-Beck disease (KBD) in Xinghai county of Qinghai province,a relative active KBD area in 2009,and to investigate their nutritional selenium level of local children and the T-2 toxin contamination level in their staple food.Methods Right hand X-ray photographs of children aged 7 - 12 in Shang,Zhong and Xia villages of Tangnaihai countryside in Xinghai county were taken.X-ray diagnosis was carried out according to the "Diagnostic Criteria of Kashin Beck Disease" (GB 16003-1995 ).Selected samples (children's hair,drinking water and their staple food) were collected according to X-ray film taken.Selenium contents in hair,drinking water and staple food samples were measured by 2,3-diaminonaphthalene fluorescence,and T-2 toxin in staple food sample was detected with enzyme-linked immunosorbent assay(ELISA) kits.Results Total X-ray detection rate of children KBD was 12.20%(31/254) and KBD positive rate of children in Xia village was up to 14.97%(22/147),Shang village was up to 9.52%(6/63),and Zhong village was up to 6.82% (3/44).The selenium level in children's body and outer environment was very low,namely,the selenium content in hair,drinking water,wheat and flour was (0.250 ± 0.136)mg/kg,(0.156 ± 0.046)μg/L,(0.0045 ± 0.0030)mg/kg,and (0.0067 ± 0.0116)mg/kg,respectively.The T-2 toxin level was relatively high in children's staple food,which was (78.91 ± 46.17)μg/kg in wheat and (47.47 ± 46.47)μg/kg in flour.Conclusions In relative active KBD areas of Xinghai county of Qinghai province,the children's selenium nutritional level is low,and the T-2 toxin contamination level in their staple food is relatively high,which is consistent with the distribution of local children's KBD.