CAJ | 학술논문

目的总结中枢神经系统Rosai-Dorfman病(RDD)的CT和MRI影像特点,增加对该病的认识,减少临床误诊率.方法结合文献回顾性分析4例病理确诊的中枢神经系统RDD患者的临床表现和影像特点.结果 2例患者行头颅CT平扫,4例患者行头颅MRI平扫加增强扫描;1例患者头颅CT显示脑水肿,1例头颅CT平扫未见异常;3例患者头颅MRI显示鞍区T1WI等或低信号,T2WI等或低信号,其中2例呈环形强化,1例呈均匀强化;1例患者右上颌窦、右鼻腔、右眶内及右颅前窝多发病灶,T1WI呈等和低混杂信号,T2WI呈等信号,呈团块样强化.4例患者病灶均基于脑膜生长.结论临床发热、头痛、血沉增快,血免疫球蛋白升高的患者,如影像检查发现颅内基于脑膜或者脊膜生长的独立或者多发病灶,特别是鞍区的病灶,应考虑到中枢神经系统RDD的可能.
목적 총결중추신경계통Rosai-Dorfman병(RDD)적CT화MRI영상특점,증가대해병적인식,감소림상오진솔.방법 결합문헌회고성분석4례병리학진적중추신경계통RDD환자적림상표현화영상특점.결과 2례환자행두로CT평소,4례환자행두로MRI평소가증강소묘;1례환자두로CT현시뇌수종,1례두로CT평소미견이상;3례환자두로MRI현시안구T1WI등혹저신호,T2WI등혹저신호,기중2례정배형강화,1례정균균강화;1례환자우상합두、우비강、우광내급우로전와다발병조,T1WI정등화저혼잡신호,T2WI정등신호,정단괴양강화.4례환자병조균기우뇌막생장.결론 림상발열、두통、혈침증쾌,혈면역구단백승고적환자,여영상검사발현로내기우뇌막혹자척막생장적독립혹자다발병조,특별시안구적병조,응고필도중추신경계통RDD적가능.
Objective To study the CT and MRI imaging features of central nervous system Rosai-Dorfman disease and to enhance knowledge and differential diagnostic ability for central nervous system Rosai-Dorfman disease.Methods The CT and MRI imaging appearances in 4 cases of pathologically proven Rosai-Dorfman disease were retrospectively evaluated and the literature of central nervous system Rosai-Dorfman disease were reviewed.Results Two cases had cranial CT scans,4 cases had cranial MRI scans,On CT scans,cerebral edema was demonstrated in one case and the other case was normaL MRI scans showed the lesions were solitary in saddle area in 3 cases,and multiple in anterior cranial fossa in 1 case.The lesions exhibited iso- to hypointensity on both T1WI and T2WI images.Following intravenous injection of contrast medium,ring-like enhancement was seen in 2 cases and homogeneous enhancement in 1 case.Nodular enhancement was seen in the case of multiple lesions in the anterior cranial fosse.All lesions were dural-based.Conclusions In patients with fever,headache,elevation of the erythrocyte sedimentation rate (ESR) and a polyclonal increase in .γ-globulins,the possibility of central nervous system Rosai-Dorfman disease should be considered when single or multiple dural-based mass lesions,especially in sellar region,were identified by CT and MRI.