CAJ | 학술논문

目的调查研究青海省海东地区平安县、乐都县、互助县等3个县4～18岁人群先天性心脏病(COHD)流行病学特征.方法对3个县97 718名4～18岁在校学生按初筛、复筛、彩色超声多普勒确定3个阶段进行调查.分析了COHD病种分布,比较了性别、各年龄段及各民族之间的患病率差异.结果检出COHD 496例.总患病率为5.076‰(496/97 718).男、女性患病率分别为5.046‰(256/50 730)和5.108‰(240/46 988),两者间差异无统计学意义(X2=0.018,P>0.05).3个县患病率分别为:乐都县5.46‰、互助县5.45‰、平安县3.64‰,不同县之间患病率差异有统计学意义(X2=10.62,P<0.01),其中乐都县、互助县患病率高于平安县(X2值分别为8.37、9.91,P<0.01).汉族的COHD患病率为5.09‰(391/76 822),藏族为5.45‰(23/4220),蒙古族为4.04‰(3/743),土族为5.02‰(57/11 345),不同民族间患病率差异无统计学意义(X2=0.33,P>0.05).在496例COHD中,房间隔缺损(ASD)与室间隔缺损(VSD)分别占37.30%和35.69%,动脉导管未闭(PDA)占22.18%.结论青海省海东3个县4～18岁人群COHD总患病率为5.076‰,不同性别、不同民族的COHD患病率基本相同.
목적 조사연구청해성해동지구평안현、악도현、호조현등3개현4～18세인군선천성심장병(COHD)류행병학특정.방법 대3개현97 718명4～18세재교학생안초사、복사、채색초성다보륵학정3개계단진행조사.분석료COHD병충분포,비교료성별、각년령단급각민족지간적환병솔차이.결과 검출COHD 496례.총환병솔위5.076‰(496/97 718).남、녀성환병솔분별위5.046‰(256/50 730)화5.108‰(240/46 988),량자간차이무통계학의의(X2=0.018,P>0.05).3개현환병솔분별위:악도현5.46‰、호조현5.45‰、평안현3.64‰,불동현지간환병솔차이유통계학의의(X2=10.62,P<0.01),기중악도현、호조현환병솔고우평안현(X2치분별위8.37、9.91,P<0.01).한족적COHD환병솔위5.09‰(391/76 822),장족위5.45‰(23/4220),몽고족위4.04‰(3/743),토족위5.02‰(57/11 345),불동민족간환병솔차이무통계학의의(X2=0.33,P>0.05).재496례COHD중,방간격결손(ASD)여실간격결손(VSD)분별점37.30%화35.69%,동맥도관미폐(PDA)점22.18%.결론 청해성해동3개현4～18세인군COHD총환병솔위5.076‰,불동성별、불동민족적COHD환병솔기본상동.
Objective To investigate the epidemiological characteristics of congenital heart disease (COHB) among 4 to 17 years old children in Haidong area of Qiaghai province. Methods All 97 718 children were surveyed with the following 3 steps: prescreening,countercheck and confirmation with color Doppler. The distribution patterns were analyzed by national groups, ages and genders respectively. Results There were 496 COHD cases detected. The total incidence was 5.076‰(496/97 718). The incidences of male and female were 5.046‰(256/50 730) and 5.108‰ (240/46 988) (X2=0.018, P>0.05). There was a significant difference between Pingan county and the others (X2=10.62, P<0.01). The highest incidence was in Ledu (5.46‰) , the incidences of Huzhu and Pingan county were 5.45‰ and 3.64‰ respectively. There was no significant difference among different national groups (X2=0.33, P>0.05). Among 496 COHD cases, the ratio of artial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PBA)were 37.30% ,35.69% and 22.18% respectively. Conclusion Total incidence of COHD was 5.076‰ in Haidong area of Qinghai province. The incidence was not different in both genders and national groups. The constitution of COHD in different counties were different.