CAJ | 학술논문

目的了解可逆性后部脑病综合征的临床及影像学特点,探讨其病因及可能的发病机制.方法回顾性分析13例可逆性后部脑病综合征患者的基础病、临床表现、影像特点,随访了解预后.结果与可逆性后部脑病综合征相关的常见疾病有各种肾病肾功能不全、妊娠及产后子痫、结缔组织病、免疫抑制剂应用等.临床表现主要为头痛、抽搐、视力下降、精神意识改变等.影像学具有多灶性、对称性、后部为主分布的特点,累及枕、顶、额的皮质及皮质下白质病灶.一般预后较好,少数较差.结论可逆性后部脑病综合征的病因机制并不相同,病变并不都可逆,寻找病因、治疗原发病对预后有决定性意义.
목적 료해가역성후부뇌병종합정적림상급영상학특점,탐토기병인급가능적발병궤제.방법 회고성분석13례가역성후부뇌병종합정환자적기출병、림상표현、영상특점,수방료해예후.결과 여가역성후부뇌병종합정상관적상견질병유각충신병신공능불전、임신급산후자간、결체조직병、면역억제제응용등.림상표현주요위두통、추휵、시력하강、정신의식개변등.영상학구유다조성、대칭성、후부위주분포적특점,루급침、정、액적피질급피질하백질병조.일반예후교호,소수교차.결론 가역성후부뇌병종합정적병인궤제병불상동,병변병불도가역,심조병인、치료원발병대예후유결정성의의.
Objective To elucidate the clinical and imaging chalaeters of reversible posterior encephalopathy syndrome(PRES)and to discuss the etiological factors and the pwbable pathogenesis.Method Retrospective analysis of basal diseases,clinical manifestations and imaging characters of 13 PRES patients was conducted with follow-ups.Results The comlmon associated diseases are various kinds of kidney disease and renal inadequacy,eclampsia of gravidity and postpartum,connective tissue disease and immunosuppressives,et al.The main clinical manifestations are headache,convulsion,poor vision,changes of psychology or consciousness.The radiological findings are multifocal,symmetrical and posteriorly dismbuted in the cerebral hemispheres involving bilateral grey and white matter abnormalities in occipital,parietal and frontal regions.The majority of patients with PRES have all excellent prognosis.Conclusion The etiological factors and pathogenesis of PRES ale different and not all of them are reversible.Thus it is decisive to take Bpecific and appropriate measures.