CAJ | 학술논문

在优化的三相中空纤维液相微萃取(3p-HFLPME)条件下,研究了6种羟基苯甲酸类化合物(HBAs)的3p-HFLPME行为;揭示了HBAs的富集因子(EF)与其正庚醇/水条件分配系数(log P_(n-heptanol/5 mmol/L HCl))、pK_a和羟基数目(N)的相关性,初步阐明了聚偏氟乙烯中空纤维对HBAs的电荷转移传递机理以及有机溶剂对HBAs的选择性萃取机理.优化的3p-HFLPME条件:以MOF 503聚偏氟乙烯中空纤维为有机溶剂支持体,正庚醇为有机相,5 mmol/L HCl体系为给体,80 mmol/L NH_3·H_2O为接受相,搅拌速度为 1 200 r/min,萃取35 min.该方法的精密度(以相对标准偏差计)小于3%,检出限为0.09～30.00 μg/L,加标回收率为93.3% ～107.1%,HBAs质量浓度为5 mg/L 时的富集因子最高达107.6倍.
재우화적삼상중공섬유액상미췌취(3p-HFLPME)조건하,연구료6충간기분갑산류화합물(HBAs)적3p-HFLPME행위;게시료HBAs적부집인자(EF)여기정경순/수조건분배계수(log P_(n-heptanol/5 mmol/L HCl))、pK_a화간기수목(N)적상관성,초보천명료취편불을희중공섬유대HBAs적전하전이전체궤리이급유궤용제대HBAs적선택성췌취궤리.우화적3p-HFLPME조건:이MOF 503취편불을희중공섬유위유궤용제지지체,정경순위유궤상,5 mmol/L HCl체계위급체,80 mmol/L NH_3·H_2O위접수상,교반속도위 1 200 r/min,췌취35 min.해방법적정밀도(이상대표준편차계)소우3%,검출한위0.09～30.00 μg/L,가표회수솔위93.3% ～107.1%,HBAs질량농도위5 mg/L 시적부집인자최고체107.6배.
Under the optimal experimental conditions of three-phase hollow fiber liquid-phase microextraction (3p-HFLPME) , the behaviors of hydroxybenzoic acids (HBAs) were investiga-ted. The correlativities between the enrichment factor (EF) of HBAs and their n-heptanol/wa-ter conditional distribution coefficients (log P_(n-heptanol/5mmol/L HCl), pK_a and the number of -OH (N); the extraction mechanism that polyvinylidene difluoride hollow fiber contributed to pro-mote the extraction efficiency by forming charge transfer compound with HBAs and the organic solvents showed notable selectivity for HBAs were elucidated. The optimal 3p-HFLPME condi-tions were: MOF 503 polyvinylidene difluoride hollow fiber as organic solvent supporter, n-hep-tanol as organic phase, 5 mmol/L HCl in the donor phase and 80 mmol/L NH_3·H_2O as the ac-ceptor phase, the HBAs were extracted for 35 min under an agitation of 1 200 r/min. It was found that the relative standard deviations were lower than 3%, the detection limits were 0. 09 -30. 00 μg/L, the average recoveries of HBAs in Calyx Kaki were 93. 3%-107. 1% and the EF of HBAs at 5 mg/L was up to 107. 6 fold.