CAJ | 학술논문

报道20例次活动期类风湿关节炎病人的99mTc-人免疫球蛋白(HIG)关节显像结果，其中16例与99mTc-MDP显像进行了对照。结果表明，所有病人 99mTc-HIG显像均为异常，表现为关节周围软组织即关节囊的放射性增高。它与临床的符合率明显高于99mTc-MDP显像；每个病人临床总分与其显像总分之间呈显著性相关( P<0.01, r=0.93)；临床累及且显像阳性的关节，其摄取放射性的多少与关节疼痛(或压痛、肿胀)程度之间，也有显著相关性(P<0.01)。99mTc-HIG关节炎症显像是一种简便、安全、无创而客观的关节炎症检查方法。它能够灵敏地探测滑膜炎症，反映疾病活动程度，帮助早期诊断类风湿关节炎，并且优于99mTc-MDP。
보도20례차활동기류풍습관절염병인적99mTc-인면역구단백(HIG)관절현상결과，기중16례여99mTc-MDP현상진행료대조。결과표명，소유병인 99mTc-HIG현상균위이상，표현위관절주위연조직즉관절낭적방사성증고。타여림상적부합솔명현고우99mTc-MDP현상；매개병인림상총분여기현상총분지간정현저성상관( P<0.01, r=0.93)；림상루급차현상양성적관절，기섭취방사성적다소여관절동통(혹압통、종창)정도지간，야유현저상관성(P<0.01)。99mTc-HIG관절염증현상시일충간 편、안전、무창이객관적관절염증검사방법。타능구령민지탐측활막염증，반영질병활동정도，방조조기진단류풍습관절염，병차우우99mTc-MDP。
This paper reported 20 cases of joint imaging in active Rheumatoid rthritis (RA) by using 99mTc labeled human immunog lobulin G(HIG), 16 of which were compared with 99mTc-MDP. Abnormal images were found in 99mTc-HIG imaging of all patients, showing increased uptake in inflammatory synovial membranes of joint capsules. The concordance of 9 9mTc-HIG imaging with clinical findings was much better than that of 99mTc-MDP bone imaging. Significant correlation was found between clinical scor e with image score, as well as uptake score of radionuclide with clinical symptoms (including pain or swelling) of the joints involved (P<0.01). It was concluded that 99mTc-HIG joint imaging was a simple, safe, noninvasive and objective method for early detection of RA. It can also demonstrate s ynovitis and assess of lammatory activity in involved joint. By the way the diagnostic value of 99mTc-HIG seems better than 99mTc-MDP bone imaging