中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2009年
18期
124-125
,共2页
地诺前列酮%米索前列醇%缩官素%临产%引产%宫颈成熟
地諾前列酮%米索前列醇%縮官素%臨產%引產%宮頸成熟
지낙전렬동%미색전렬순%축관소%임산%인산%궁경성숙
Dinoprostone%Misoprostol%Oxytocin%labor starting%Induced labor%Cervical ripening
目的 比较地诺前列酮(普贝生)、米索前列醇及缩宫素促宫颈成熟及引产的临床效果.方法 随机将180例单活胎具备引产指征的初产妇分为三组,普贝生组60例,阴道后穹隆放置普贝生;米索前列醇组60例.阴道后穹隆放置米索前列醇.缩宫素组60例静脉输注缩官素.结果 用药8h后,普贝生组官颈成熟度明显优于缩宫素组,平均临产时间、破膜时间、分娩时间均明显短于缩宫素组.引产成功率:普贝生组达80.0%,明显高于缩官素组的20.0%(P<0.01).普贝生组促宫颈成熟及引产效果与米索前列醇组相近(P>0.05).结论 普贝生是一种安全、有效的促宫颈成熟和引产的药物.
目的 比較地諾前列酮(普貝生)、米索前列醇及縮宮素促宮頸成熟及引產的臨床效果.方法 隨機將180例單活胎具備引產指徵的初產婦分為三組,普貝生組60例,陰道後穹隆放置普貝生;米索前列醇組60例.陰道後穹隆放置米索前列醇.縮宮素組60例靜脈輸註縮官素.結果 用藥8h後,普貝生組官頸成熟度明顯優于縮宮素組,平均臨產時間、破膜時間、分娩時間均明顯短于縮宮素組.引產成功率:普貝生組達80.0%,明顯高于縮官素組的20.0%(P<0.01).普貝生組促宮頸成熟及引產效果與米索前列醇組相近(P>0.05).結論 普貝生是一種安全、有效的促宮頸成熟和引產的藥物.
목적 비교지낙전렬동(보패생)、미색전렬순급축궁소촉궁경성숙급인산적림상효과.방법 수궤장180례단활태구비인산지정적초산부분위삼조,보패생조60례,음도후궁륭방치보패생;미색전렬순조60례.음도후궁륭방치미색전렬순.축궁소조60례정맥수주축관소.결과 용약8h후,보패생조관경성숙도명현우우축궁소조,평균임산시간、파막시간、분면시간균명현단우축궁소조.인산성공솔:보패생조체80.0%,명현고우축관소조적20.0%(P<0.01).보패생조촉궁경성숙급인산효과여미색전렬순조상근(P>0.05).결론 보패생시일충안전、유효적촉궁경성숙화인산적약물.
Objective To comparatively study on clinical effectiveness of dinoprostone(propess). Misoprostol and oxytocin in promoting cervical ripening and induced lbor. Methods A tolal of 180 patients with singleton gestation and with indications for labor induction were randomly assigned to 3 groups, respectively. Women were randomiged to receive propess 10mg(dinoprostone group) or misoprostal 25ug (misoprostal group) in posterion vaginal fomix and intravenous 0.5%～1% oxytocin (oxytocin group). Results Propess was better than oxytocin in promoting cervical ripening. The time to labor starting, membrane rapture and delivery was significantly shorter in the propess group than in the oxytoein group after applying medicine 24h later,the successful induced labor rate were 80.0% and 20.0%(P <0.01). The effectiveness of the propess group and the misoprostol group in promoting cervical ripening and induced labor was similar(P>0.05).Conclusion Propess can be used in promoting cervical ripening and induced labor safely and effectively.
