CAJ | 학술논문

目的应用光学相干断层扫描(optical coherence to mo graphy,OCT)和多焦视网膜电流图(multifocal electmretinogram.mfERG),随访观察曲安奈德玻璃体腔注射治疗视网膜分支静脉阻塞继发黄斑水肿患者的疗效.方法对28例视网膜分支静脉阻塞继发黄斑水肿患者,于曲安奈德玻璃体腔注射前后进行视力及OCT、nfERG检查,对比分析视力与视网膜神经上皮层厚度及黄斑区视功能变化.结果 :与治疗前相比,视力均有不同幅度的提高;视网膜神经上皮层厚度平均厚度明显降低;中心凹处(1环)P1波振幅密度增加,均与治疗前比较差异具有统计学意义(P<0.05).结论应用OCT、mfERG随访检查,司以对病情的发展进行有效的跟踪观察,为曲安奈德玻璃体腔注射治疗的疗效提供可靠的依据.
목적 응용광학상간단층소묘(optical coherence to mo graphy,OCT)화다초시망막전류도(multifocal electmretinogram.mfERG),수방관찰곡안내덕파리체강주사치료시망막분지정맥조새계발황반수종환자적료효.방법 대28례시망막분지정맥조새계발황반수종환자,우곡안내덕파리체강주사전후진행시력급OCT、nfERG검사,대비분석시력여시망막신경상피층후도급황반구시공능변화.결과 :여치료전상비,시력균유불동폭도적제고;시망막신경상피층후도평균후도명현강저;중심요처(1배)P1파진폭밀도증가,균여치료전비교차이구유통계학의의(P<0.05).결론 응용OCT、mfERG수방검사,사이대병정적발전진행유효적근종관찰,위곡안내덕파리체강주사치료적료효제공가고적의거.
Objective To observe the therapeutic efficacy of intravitreal injection of triamcinolone aeetonide (IVTA) for maeular edema secondary to B RVO determined by optic coherence tomography (OCT)and multifoeal electroretinogram (mfERG). Methods TA was injected intravitreally in 28 eyes of 28 patients with maeular edema secondary to BRVO determined by OCT and mfERG. The change of visual acuity,the maeular thickness measured by OCT and maeular function by rnIERG were recorded and analyzed. Results Vi-sual acuity was improved significantly at the end of the follow up. The average macular thickness and the aver-age P1 amplitude was improved after treatment, which had statistical significance (P <0.05). Conelusion Ⅳ-TA could alleviate the macular edema secondary to BRVO. OCT and mfERG were useful means to evaluate the macular changes before and after IVTA for BRVO.