CAJ | 학술논문

目的研究超声引导针吸活检在术前判断乳腺癌腋窝淋巴结转移中的应用,评价该方法的可行性和诊断的准确率. 方法对40例腋窝触诊阴性的高度可疑乳腺癌患者的40个腋窝淋巴结进行超声引导针吸活检,将结果与前哨淋巴结活检或腋窝淋巴结清扫的组织学病理结果进行对照.分析超声引导针吸活检判断乳腺癌腋窝淋巴结转移的敏感性、特异性、阳性预测值、阴性预测值和诊断准确率.结果 40例患者全部经病理证实为浸润性乳腺癌.超声引导针吸活检判断腋窝淋巴结转移的敏感性、特异性、阳性预测值、阴性预测值和诊断准确率分别为52.2%、100%、100%、60.7%、72.5%.有12例(30%)术前细针穿刺活检阳性的患者避免了前哨活检,直接接受了腋窝清扫.结论应用超声引导针吸活检在术前判断乳腺癌的腋窝淋巴结转移情况创伤小、特异性高,可以避免部分患者接受前哨淋巴结活检术.
목적 연구초성인도침흡활검재술전판단유선암액와림파결전이중적응용,평개해방법적가행성화진단적준학솔. 방법대40례액와촉진음성적고도가의유선암환자적40개액와림파결진행초성인도침흡활검,장결과여전초림파결활검혹액와림파결청소적조직학병리결과진행대조.분석초성인도침흡활검판단유선암액와림파결전이적민감성、특이성、양성예측치、음성예측치화진단준학솔.결과 40례환자전부경병리증실위침윤성유선암.초성인도침흡활검판단액와림파결전이적민감성、특이성、양성예측치、음성예측치화진단준학솔분별위52.2%、100%、100%、60.7%、72.5%.유12례(30%)술전세침천자활검양성적환자피면료전초활검,직접접수료액와청소.결론 응용초성인도침흡활검재술전판단유선암적액와림파결전이정황창상소、특이성고,가이피면부분환자접수전초림파결활검술.
Objective To study the utilization of preoperative ultrasound-guided fine-needle aspiration(USFNA) for axillary lymphnode(ALN) metastasis in breast cancer and to evaluate the feasibility and accuracy of the technique. Methods Forty ALNs in 40 armpit negative palpation highly suspective breast cancer patients underwent USFNA. The cytopathological results were compared with the histopathological results of sentinel lymphnode(SLN) biopsy or axillary lymphnode dissection(ALND). The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and diagnostic accuracy of USFNA for the ALN metastasis were analysed. Results All the 40 patients were confirmed with breast cancer by pathology. Sensitivity of USFNA was 52. 2%, specificity was 100%, PPV was 100%,NPV was 60. 7% and diagnostic accuracy was 72. 5%. 12(30% ) patients with positive cytology proceeded to ALND, avoiding SLN biopsy. Conclusions USFNA is a minimally invasive, highly specified technique for prediction of breast cancer ALN metastasis before operation.