CAJ | 학술논문

DNA折纸术是近年来提出的一种全新的DNA自组装的方法,是DNA纳米技术与DNA自组装领域的一个重大进展.与传统的DNA自组装技术不同,DNA折纸术通过将一条长的DNA单链(通常为基因组DNA)与一系列经过设计的短DNA片段进行碱基互补,能够可控地构造出高度复杂的纳米图案或结构,在新兴的纳米领域中具有广泛的潜在应用.本文在介绍DNA折纸术相关原理的基础上,就DNA折纸术的起源、发展及其在DNA芯片、纳米元件与材料等领域的潜在应用进行了概述,探讨了DNA折纸术未来可能的发展方向.
DNA절지술시근년래제출적일충전신적DNA자조장적방법,시DNA납미기술여DNA자조장영역적일개중대진전.여전통적DNA자조장기술불동,DNA절지술통과장일조장적DNA단련(통상위기인조DNA)여일계렬경과설계적단DNA편단진행감기호보,능구가공지구조출고도복잡적납미도안혹결구,재신흥적납미영역중구유엄범적잠재응용.본문재개소DNA절지술상관원리적기출상,취DNA절지술적기원、발전급기재DNA심편、납미원건여재료등영역적잠재응용진행료개술,탐토료DNA절지술미래가능적발전방향.
DNA origami is a new DNA self-assembly method proposed recently and is a major innovation in the field of DNA nanotechnology and self-assembly. Compared to traditional DNA self-assembly, DNA origami uses a long single-stranded genomic DNA with a series of short complementary single-strands DNA, and it can construct more complex and more controllable nanopatterns or structures and possess a wide range of potential application in the emerging field of nanotechnology. The authors briefly introduced the principles of DNA origami, then reviewed the origin and development of DNA origami and its potential application in the field of DNA chip, nanocomponents and nanomaterials. In the end we discussed the future directions of such technology.