中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2012年
1期
14-18
,共5页
王智凤%孙晓红%宋志强%赵煜%柯美云%朱有玲%王学勤%罗金燕%谢小平%候晓华%邹多武
王智鳳%孫曉紅%宋誌彊%趙煜%柯美雲%硃有玲%王學勤%囉金燕%謝小平%候曉華%鄒多武
왕지봉%손효홍%송지강%조욱%가미운%주유령%왕학근%라금연%사소평%후효화%추다무
食管括约肌,下段%年龄因素%食管胃接合处%测压法%蠕动
食管括約肌,下段%年齡因素%食管胃接閤處%測壓法%蠕動
식관괄약기,하단%년령인소%식관위접합처%측압법%연동
Esophageal sphincter, lower%Age factors%Esophageogastric junction%manometry%Peristalsis
目的 建立不同年龄组食管动力参数正常值及测定方法.方法 应用气液压毛细灌注系统测定3个不同年龄组(Ⅰ组18～39岁,Ⅱ组40～59岁,Ⅲ组≥60岁)健康志愿者食管动力参数.同时观察本测定方法对下食管括约肌(LES)检测的重复性和稳定性.结果 实际入组162名,Ⅰ组62名,Ⅱ组73名,Ⅲ组27名.三组间下食管括约肌长度(LESL)、呼气末下食管括约肌压力(LESP)、LESP平均值、残余压、下食管括约肌松弛率(LESRR)差异无统计学意义(P＞0.05).Ⅰ组吸气末LESP为(28.98±1.11) mmHg,明显低于Ⅲ组[(34.35±1.96)mmHg,P＜0.05].Ⅰ组跨膈压为(9.55±0.62) mmHg,明显低于Ⅱ组[(13.05±0.76) mmHg,P＜0.05].三组食管体部远端和近端收缩波幅和时限差异无统计学意义(P＞0.05).Ⅲ组上食管括约肌压力( UESP)明显低于Ⅰ组、Ⅱ组(P＜0.05).重复性比较,Ⅰ组、Ⅱ组第2次呼气末LESP明显高于第1次(P＜0.05).远端食管蠕动收缩波幅女性明显高于男性(P＜0.05),近端食管蠕动收缩波幅女性与男性无明显差别(P＞0.05).结论 得到不同年龄组食管动力参数的正常值.LES的动力参数不随年龄的增长而变化.而食管体部蠕动收缩能力在40～59岁年龄组最强.老年人UESP明显下降.检测前让受试者有足够的适应时间,有利于得到准确、可靠的LES的动力参数.
目的 建立不同年齡組食管動力參數正常值及測定方法.方法 應用氣液壓毛細灌註繫統測定3箇不同年齡組(Ⅰ組18～39歲,Ⅱ組40～59歲,Ⅲ組≥60歲)健康誌願者食管動力參數.同時觀察本測定方法對下食管括約肌(LES)檢測的重複性和穩定性.結果 實際入組162名,Ⅰ組62名,Ⅱ組73名,Ⅲ組27名.三組間下食管括約肌長度(LESL)、呼氣末下食管括約肌壓力(LESP)、LESP平均值、殘餘壓、下食管括約肌鬆弛率(LESRR)差異無統計學意義(P＞0.05).Ⅰ組吸氣末LESP為(28.98±1.11) mmHg,明顯低于Ⅲ組[(34.35±1.96)mmHg,P＜0.05].Ⅰ組跨膈壓為(9.55±0.62) mmHg,明顯低于Ⅱ組[(13.05±0.76) mmHg,P＜0.05].三組食管體部遠耑和近耑收縮波幅和時限差異無統計學意義(P＞0.05).Ⅲ組上食管括約肌壓力( UESP)明顯低于Ⅰ組、Ⅱ組(P＜0.05).重複性比較,Ⅰ組、Ⅱ組第2次呼氣末LESP明顯高于第1次(P＜0.05).遠耑食管蠕動收縮波幅女性明顯高于男性(P＜0.05),近耑食管蠕動收縮波幅女性與男性無明顯差彆(P＞0.05).結論 得到不同年齡組食管動力參數的正常值.LES的動力參數不隨年齡的增長而變化.而食管體部蠕動收縮能力在40～59歲年齡組最彊.老年人UESP明顯下降.檢測前讓受試者有足夠的適應時間,有利于得到準確、可靠的LES的動力參數.
목적 건립불동년령조식관동력삼수정상치급측정방법.방법 응용기액압모세관주계통측정3개불동년령조(Ⅰ조18～39세,Ⅱ조40～59세,Ⅲ조≥60세)건강지원자식관동력삼수.동시관찰본측정방법대하식관괄약기(LES)검측적중복성화은정성.결과 실제입조162명,Ⅰ조62명,Ⅱ조73명,Ⅲ조27명.삼조간하식관괄약기장도(LESL)、호기말하식관괄약기압력(LESP)、LESP평균치、잔여압、하식관괄약기송이솔(LESRR)차이무통계학의의(P＞0.05).Ⅰ조흡기말LESP위(28.98±1.11) mmHg,명현저우Ⅲ조[(34.35±1.96)mmHg,P＜0.05].Ⅰ조과격압위(9.55±0.62) mmHg,명현저우Ⅱ조[(13.05±0.76) mmHg,P＜0.05].삼조식관체부원단화근단수축파폭화시한차이무통계학의의(P＞0.05).Ⅲ조상식관괄약기압력( UESP)명현저우Ⅰ조、Ⅱ조(P＜0.05).중복성비교,Ⅰ조、Ⅱ조제2차호기말LESP명현고우제1차(P＜0.05).원단식관연동수축파폭녀성명현고우남성(P＜0.05),근단식관연동수축파폭녀성여남성무명현차별(P＞0.05).결론 득도불동년령조식관동력삼수적정상치.LES적동력삼수불수년령적증장이변화.이식관체부연동수축능력재40～59세년령조최강.노년인UESP명현하강.검측전양수시자유족구적괄응시간,유리우득도준학、가고적LES적동력삼수.
Objective To establish normative values of esophageal manometry in different age groups and standard test method.Methods The values of esophageal manometry were tested in healthy subjects of 3 different age groups (Group Ⅰ: 18-39 years,Group Ⅱ: 40-59 years,Group Ⅲ:≥60 years) with pneumohydraulic capillary perfusion system.The repeatability and stability of this method in lower esophageal sphincter (LES) testing were observed. Results There were no significant differences of LES length (LESL),LES pressure (LESP) at the end of expiration,average LESP,residual pressure of LES and LES relaxation rate (LESRR) in three groups (P＞0.05).The LESP at the end of inspiration in Group Ⅰ (28.98± 1.11 ) mm Hg was significantly lower than that of Group Ⅲ (34.35±1.96) mm Hg (P＜0.05).Trandiaphragmatic pressure (Pdi) in Group Ⅰ (9.55±0.62) mm Hg was significantly lower than that of Group Ⅱ (13.05±0.76) mm Hg (P＜0.05).There were no significant differences in contraction amplitude and duration of proximal and distant esophagus in 3 groups (P＞0.05).UES pressure (UESP) of Group Ⅲ was significantly lower than that of Group Ⅰ and Ⅱ (P＜0.05).As for repeatability,the second recording of LESP in Group Ⅰ and Ⅱ were significantly higher than first recording (P＜0.05).Amplitude of distant esophageal peristaltic contraction (DEPC) of female was significantly higher than of male (P＜0.05).However,there was no significant difference in amplitude of proximal esophageal peristaltic contraction (PEPC)between femal and male (P＞0.05).Conclusions The normative values of esophageal manometry in different age groups have been obtained.The dynamic parameters of LES do not change with age.Between age 40 to 59 years old,the contraction of esophageal body is strongest.UESP decreases significantly in old people.If the subjects have enough time to adapt before test,it will help to get accurate and reliable dynamic parameters of LES.
