CAJ | 학술논문

背景:钛合金种植体已经广泛应用于临床,但作者所查对于牙种植体植入后的耐腐蚀性,尤其在不同生理电解溶液中耐腐蚀行为的对比报道很少.目的:对比观察医用钛合金在生理盐水,模拟人工唾液,模拟人工体液3种电解溶液中的耐腐蚀情况.设计、时间及地点:随机分组设计,对比观察实验,于2008-11/2009-03在兰州大学口腔医学院和中国科学院兰州化学物理研究所固体润滑实验室完成.材料:医用钛合金(Ti-6Al-4V)制备成10mm×10mm×1 mm板片,随机分为3组,每组10个.方法:利用电化学方法分析医用钛合金在生理盐水,模拟人工唾液,模拟人工体液中的腐蚀情况,扫面电镜观察腐蚀表面形貌,CA-A型接触角测试仪测试钛合金表面被腐蚀后接触角的变化.主要观察指标:医用钛合金在3种生理电解液中腐蚀4 d后的阳极极化曲线、表面形貌、接触角.结果:钛合金在3种生理电解液中的腐蚀情况依次是:模拟人工唾液>模拟人工体液>生理盐水.扫面电锖观察表明,医用钛合余绎生理盐水腐蚀后,表面出现了许多腐蚀孔,经模拟人体体液腐蚀后,表面变得粗糙不平整,腐蚀孔数目变化不大,钛合金经人工唾液腐蚀后,腐蚀孔数目增多,部分腐蚀孔孔径明显增大.经3种生理电解液腐蚀后,钛合金表面接触角都减小.结论:医用钛合金在人工唾液中的腐蚀最严重,在临床应用中应给予相应的防范措施.
배경:태합금충식체이경엄범응용우림상,단작자소사대우아충식체식입후적내부식성,우기재불동생리전해용액중내부식행위적대비보도흔소.목적:대비관찰의용태합금재생리염수,모의인공타액,모의인공체액3충전해용액중적내부식정황.설계、시간급지점:수궤분조설계,대비관찰실험,우2008-11/2009-03재란주대학구강의학원화중국과학원란주화학물리연구소고체윤활실험실완성.재료:의용태합금(Ti-6Al-4V)제비성10mm×10mm×1 mm판편,수궤분위3조,매조10개.방법:이용전화학방법분석의용태합금재생리염수,모의인공타액,모의인공체액중적부식정황,소면전경관찰부식표면형모,CA-A형접촉각측시의측시태합금표면피부식후접촉각적변화.주요관찰지표:의용태합금재3충생리전해액중부식4 d후적양겁겁화곡선、표면형모、접촉각.결과:태합금재3충생리전해액중적부식정황의차시:모의인공타액>모의인공체액>생리염수.소면전창관찰표명,의용태합여역생리염수부식후,표면출현료허다부식공,경모의인체체액부식후,표면변득조조불평정,부식공수목변화불대,태합금경인공타액부식후,부식공수목증다,부분부식공공경명현증대.경3충생리전해액부식후,태합금표면접촉각도감소.결론:의용태합금재인공타액중적부식최엄중,재림상응용중응급여상응적방범조시.
BACKGROUND: Titanium alloy implant has been widely used in the clinic. But there are few reports addressing on corrosion performance of medical titanium alloy dental implant, in particular in different physiological electrolytes. OBJECTIVE: To investigate the corrosion behaviors of medical titanium alloys in physiological saline, simulated saliva, and simulated body fluid. DESIGN, TIME AND SETTING: A randomized grouping, controlled observation was performed at the School of Stomatology, Lanzhou University and State Key Laboratory of Solid Lubdcation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences between November 2008 and March 2009. MATERIALS: Medical titanium alloys (Ti-6Al-4V) were cut into 10 mm×10 min×1 mm sheets and were randomly divided into 3 groups, with 10 sheets in each group. METHODS: Corrosion performance of titanium alloys in physiological saline, simulated saliva, and simulated body fluid was investigated using electrochemical measurements. Following electrochemical corrosion, surface morphologies and wettability of samples were also observed using scanning electron microscope and CA-A type contact angle tester. MAIN OUTCOME MEASURES: Tafel curve, surface morphology, and contact angle of medical titanium alloys in three physiological electrolytes after 4 days of electrochemical corrosion. RESULTS: The corrosion of titanium alloys was most severe in simulated saliva, followed by simulated body fluid, and mildest in physiological saline. Scanning electron microscope results demonstrated that medical titanium alloy surface exhibited many holes after corrosion by physiological saline, showed rough surface with a slightly changed number of holes after corrosion by simulated body fluid, and presented with an increased number of holes, with aperture greatly increased in some holes after corrosion by simulated saliva. The contact angles of titanium alloys were all reduced after corrosion of three electrolytes. CONCLUSION: The corrosion of titanium alloy was most serious in simulated saliva. Thus, corresponding protection measures should be given in clinical application.