CAJ | 학술논문

目的动物实验的角度分析跟腱断裂术后早期运动与制动状态下组织学差异,为术后早期运动提供组织学证据.方法将新西兰家兔随机分成正常组,早期运动组,石膏固定组.造模后对家兔跟腱进行组织学检查,寻找组织学差异.结果家兔跟腱HE染色后,光镜下观察,早期运动组胶原纤维更粗[(8.417±1.649)μm vs(6.818±1.025)μm,t=2.76,P＜0.05],排列更整齐,成纤维细胞更成熟;电镜下观察,早期运动组胶原原纤维的直径更大,差异有统计学意义[(26.915±2.123)nm vs(21.725±3.768)nm,t=4.12,P＜0.01].结论术后早期运动能够促进跟腱的组织学愈合.
목적 동물실험적각도분석근건단렬술후조기운동여제동상태하조직학차이,위술후조기운동제공조직학증거.방법 장신서란가토수궤분성정상조,조기운동조,석고고정조.조모후대가토근건진행조직학검사,심조조직학차이.결과 가토근건HE염색후,광경하관찰,조기운동조효원섬유경조[(8.417±1.649)μm vs(6.818±1.025)μm,t=2.76,P＜0.05],배렬경정제,성섬유세포경성숙;전경하관찰,조기운동조효원원섬유적직경경대,차이유통계학의의[(26.915±2.123)nm vs(21.725±3.768)nm,t=4.12,P＜0.01].결론 술후조기운동능구촉진근건적조직학유합.
Objective To offer the histological proof of rabbits rupture repair after early mobilization.Method New zealand rabbits were random divided into 3 groups, including normal group, mobilization group (the experimental group) , and immobilization group.All rabbits' achilles tendons were inspected, and the histological difference were observed under light microscope and electron microscope respectively.Result The collagen fibers of the achilles tendons in the mobilization group under light microscope showed that it arrayed more regularly than in immobilization group.Fibroblasts were more maturate.The diameters of collagen fibrils under electron microscope in mobilization group were thicker[(8.417 ± 1.649)μm vs (6.818 ± 1.025)μm, t = 2.76, P ＜ 0.05] than immobilization group.The results showed statistical significance[(26.915 ±2.123)nm vs (21.725 ±3.768)nm, t =4.12, P ＜0.01].Conclusion Early mobilization after operation can promote the histological healing of achiles tendon.