CAJ | 학술논문

目的探讨青少年空腹血糖受损(wG)与体脂分布的关系.方法通过分层整群随机抽样,测定3874例13～18岁青少年身高、体重、腰围、臀围和空腹血糖(FPG)水平,通过问卷调查了解其父母糖尿病患病情况.根据F1PG水平,分为空腹血糖正常组(FPG＜5.6 mmol/L,n=3738)和空腹血糖受损组(5.6 mmol/L≤FPG＜7.0 mmol/L,n=136).结果两组间各体脂指标比较,应用协方差分析校正性别、年龄后,空腹血糖受损组体重指数、腰围、腰围/身高比和腰臀比均高于空腹血糖正常组,组间比较差异有统计学意义(P＜0.05).应用偏相关分析校正年龄、性别后,BMI、腰围、腰臀比及腰围/身高比均与FPG呈正相关(P＜0.05),其中腰围/身高比的r'值最大(r'=0.0925).对FPG的多元线性回归分析,最佳模型引入年龄(β=-0.102,P＜0.05)、糖尿病家族史(β=0.186,P＜0.05)和腰围/身高比(β=0.842,P＜0.05).结论中心性肥胖与青少年空腹血糖受损关系密切,腰围/身高比是描述青少年中心性肥胖的有效指标,是青少年空腹血糖受损的独立危险因素.
목적 탐토청소년공복혈당수손(wG)여체지분포적관계.방법 통과분층정군수궤추양,측정3874례13～18세청소년신고、체중、요위、둔위화공복혈당(FPG)수평,통과문권조사료해기부모당뇨병환병정황.근거F1PG수평,분위공복혈당정상조(FPG＜5.6 mmol/L,n=3738)화공복혈당수손조(5.6 mmol/L≤FPG＜7.0 mmol/L,n=136).결과 량조간각체지지표비교,응용협방차분석교정성별、년령후,공복혈당수손조체중지수、요위、요위/신고비화요둔비균고우공복혈당정상조,조간비교차이유통계학의의(P＜0.05).응용편상관분석교정년령、성별후,BMI、요위、요둔비급요위/신고비균여FPG정정상관(P＜0.05),기중요위/신고비적r'치최대(r'=0.0925).대FPG적다원선성회귀분석,최가모형인입년령(β=-0.102,P＜0.05)、당뇨병가족사(β=0.186,P＜0.05)화요위/신고비(β=0.842,P＜0.05).결론 중심성비반여청소년공복혈당수손관계밀절,요위/신고비시묘술청소년중심성비반적유효지표,시청소년공복혈당수손적독립위험인소.
Objective To investigate the relationship between impaired fasting glucose(IFG) and the distribution of body fat in adolescents.Methods Stratified cluster sampling was used to select 3874 adolescents aged 13-18 years for this cress-sectional study.Measurements included height,weight,waist circumference,hip circumference and fasting plasma glucose (FPG).Family history of diabetes was determined by using a serf-administered questionnaire.Participants were divided into normal fasting glucose group(FPG＜5.6 mmol/L,n=3738) and impaired fasting glucose group (5.6 mmol/L≤FPG ＜ 7.0 mmoL/L,n=136) according to their FPG levels. Results (1) After adjusting for age and sex using covariance analysis,the impaired fasting glucose group showed increased levels of body mass index,weight circumference,waist/hip ratio,waist/height ratio,as compared to the normal fasting glucose group (P＜ 0.05).(2) After the age and gender were adjusted,body mass index,weight circumference,waist/hip ratio and waist/height ratio were positively correlated with FPG level (P＜0.05).Among the partial relation coefficients, that between waist/height ratio and FPG(r'=0.0925) was the highest (3) In multiple regression analyses,age (β=-0.102,P＜0.05),family history of diabetes (β=0.186,P＜0.05) and waist/height ratio (β=0.842,P＜0.05) were consistently associated with FPG.Conclusion Central obesity was an important predictor of IFG in adolescents.Waist/height ratio may be an useful index of central obesity and an important predictor of IFG in adolescents.