CAJ | 학술논문

目的探讨肾结石合并肾盂鳞状细胞癌的早期诊断与治疗.方法报告肾结石合并肾盂鳞状细胞癌2例,结合相关文献探讨其早期诊断及治疗方法.结果 2例均有典型肾绞痛病史及合并血尿,CT检查提示肾盂癌2例.2例术中经冰冻病理确诊后,行根治性患肾切除术,1例术后行全身化疗,5个月后死于全身衰竭,另一类术后随访18个月无复发.2例病理诊断均为鳞状细胞癌.结论肾结石合并肾盂鳞状细胞癌恶性程度高、预后差,临床表现缺乏特异性,易误诊和漏诊,提高对本病的认识,对可疑病例进行多项必要的辅助检查,有助于明确诊断.治疗以根治性患肾切除为主.
목적 탐토신결석합병신우린상세포암적조기진단여치료.방법 보고신결석합병신우린상세포암2례,결합상관문헌탐토기조기진단급치료방법.결과 2례균유전형신교통병사급합병혈뇨,CT검사제시신우암2례.2례술중경빙동병리학진후,행근치성환신절제술,1례술후행전신화료,5개월후사우전신쇠갈,령일류술후수방18개월무복발.2례병리진단균위린상세포암.결론 신결석합병신우린상세포암악성정도고、예후차,림상표현결핍특이성,역오진화루진,제고대본병적인식,대가의병례진행다항필요적보조검사,유조우명학진단.치료이근치성환신절제위주.
Objective To investigate the early diagnosis and treatment of renal calculi associated with squamous cell carcinoma of the renal pelvis. Methods 2 cases of squamous cell carcinoma of the renal pelvis associated with renal calculi were reported in our department. The literature was reviewed to discuss the early diagnosis and treatment. Results Both of the 2 patients presented with typical renal colic and hematuria,2 cases of renal pelvic tumor were diagnosed by CT. Radical nephrectomy was performed for the 2 patients after squamous cell carcinoma was detected with frozen section during operation. One patient received systemic chemotherapy and died from cancer collapse after 5 months,the other developed no recurrence during follow-up of 18 months. Both of the 2 cases were proved squamous cell carcinoma in pathology after operation. Conclusion Squamous cell carcinoma of the renal pelvis associated with renal calculi has an aggressive behavior and unfavourable prognosis, and it may be easily misdiagnosised and missed because its clinical manifestation is lack of specificit. Once a case is suspected squamous cell carcinoma of the renal pelvis, many necessary assistance examinations should be performed for diagnosis and the optimal treatment is radical nephrectomy.