CAJ | 학술논문

为适应油气田现场化学剂使用时QHSE发展趋势，确保油气田现场用化学助剂安全无毒无污染的性能特点，采用小白鼠毒性测试研究了现场用化学剂的毒性。通过采用灌胃的方法，研究了CPI-5缓蚀剂对小鼠的急性毒性。一次性给药后连续观察7天，检测CPI-5缓蚀剂对小鼠的急性毒性作用，包括最小致死剂量和半数致死量。实验结果表明：CPI-5缓蚀剂灌胃给小鼠的最小致死剂量约为14．9v,／kg体重，半数致死剂量约为30．45g／kg体重，因此CPI-5缓蚀剂属于无毒或微毒的化学剂，能够适用于油气田现场推广，同时无毒无害缓蚀剂运用于现场对于改善现场操作环境和保证员工的健康具有重要的意义。
위괄응유기전현장화학제사용시QHSE발전추세，학보유기전현장용화학조제안전무독무오염적성능특점，채용소백서독성측시연구료현장용화학제적독성。통과채용관위적방법，연구료CPI-5완식제대소서적급성독성。일차성급약후련속관찰7천，검측CPI-5완식제대소서적급성독성작용，포괄최소치사제량화반수치사량。실험결과표명：CPI-5완식제관위급소서적최소치사제량약위14．9v,／kg체중，반수치사제량약위30．45g／kg체중，인차CPI-5완식제속우무독혹미독적화학제，능구괄용우유기전현장추엄，동시무독무해완식제운용우현장대우개선현장조작배경화보증원공적건강구유중요적의의。
Base on the QHSE of chemicals used in the oil and gas field, in order to prevent the oil and gas field from polluting, the toxicity of the chemicals testing on mice was studied. The acute oral toxicity of CPI-5 corrosion inhibitor on mouse was tested by a disposable dosage giving chemical after giving chemical 7-days and continuous observation on mousse carried out for the minimum lethal dose ＆ median lethal dose analysis of CPI-5 corrosion inhibitor. The result shows that the minimum lethal dose ＆ LD50 of CPI-5 corrosion inhibitor were about 14. 9g/kg weight and 30. 45g/kg weight, so CPI-5 corro- sion inhibitor was defined as non-toxic or low toxicity, and it could be widely used in oil and gas field. Due to the non-tixic or low toxicity of the corrosion inhibitor in the oil and gas field, it was very important to operation environment and healthy of employees.