中国医药
中國醫藥
중국의약
CHINA MEDICINE
2010年
1期
40-42
,共3页
神经症%甜梦胶囊%地西泮%氟哌噻吨美利曲辛
神經癥%甜夢膠囊%地西泮%氟哌噻噸美利麯辛
신경증%첨몽효낭%지서반%불고새둔미리곡신
Neuroses%Tianmeng capsule%Valium%Flupentixol-Melitracen
目的 比较甜梦胶囊联合氟哌噻吨美利曲辛和地两泮联合氟哌噻吨美利曲辛治疗神经症的疗效.方法 将符合入组标准的神经症患者120例完全随机分为甜梦胶囊联合氟哌噻吨美利曲辛的(甜梦胶囊)组和地西泮联合氟哌噻吨美利曲辛的(地西泮)组,各60例,两组年龄和性别比较差异统计学意义(P>0.05).在用药前及服药后1、2、8周进行汉密尔顿抑郁量表(HAMD)、听觉事件相关电位(ERPs)P300、皮肤交感反应(SSR)、匹兹堡睡眠质量指数(PSQI)检测,比较两组HAMD、ERPs P300、SSR、PSQI的差异.结果 甜梦胶囊组在治疗1周、2周及8周后的HAMD评分均明显低于地西泮组(P<0.01),同时甜梦胶囊组的ERPs P300及SSR潜伏期明显缩短,波幅明显升高,与地西泮组比较差异有统计学意义(P<0.01).结论 甜梦胶囊组的患者HAMD、ERPs P300、SSR、PSQI等指标均有明显改善,提示甜梦胶囊比地西泮能更为有效地延长患者的睡眠时间,改善睡眠质量.
目的 比較甜夢膠囊聯閤氟哌噻噸美利麯辛和地兩泮聯閤氟哌噻噸美利麯辛治療神經癥的療效.方法 將符閤入組標準的神經癥患者120例完全隨機分為甜夢膠囊聯閤氟哌噻噸美利麯辛的(甜夢膠囊)組和地西泮聯閤氟哌噻噸美利麯辛的(地西泮)組,各60例,兩組年齡和性彆比較差異統計學意義(P>0.05).在用藥前及服藥後1、2、8週進行漢密爾頓抑鬱量錶(HAMD)、聽覺事件相關電位(ERPs)P300、皮膚交感反應(SSR)、匹玆堡睡眠質量指數(PSQI)檢測,比較兩組HAMD、ERPs P300、SSR、PSQI的差異.結果 甜夢膠囊組在治療1週、2週及8週後的HAMD評分均明顯低于地西泮組(P<0.01),同時甜夢膠囊組的ERPs P300及SSR潛伏期明顯縮短,波幅明顯升高,與地西泮組比較差異有統計學意義(P<0.01).結論 甜夢膠囊組的患者HAMD、ERPs P300、SSR、PSQI等指標均有明顯改善,提示甜夢膠囊比地西泮能更為有效地延長患者的睡眠時間,改善睡眠質量.
목적 비교첨몽효낭연합불고새둔미리곡신화지량반연합불고새둔미리곡신치료신경증적료효.방법 장부합입조표준적신경증환자120례완전수궤분위첨몽효낭연합불고새둔미리곡신적(첨몽효낭)조화지서반연합불고새둔미리곡신적(지서반)조,각60례,량조년령화성별비교차이통계학의의(P>0.05).재용약전급복약후1、2、8주진행한밀이돈억욱량표(HAMD)、은각사건상관전위(ERPs)P300、피부교감반응(SSR)、필자보수면질량지수(PSQI)검측,비교량조HAMD、ERPs P300、SSR、PSQI적차이.결과 첨몽효낭조재치료1주、2주급8주후적HAMD평분균명현저우지서반조(P<0.01),동시첨몽효낭조적ERPs P300급SSR잠복기명현축단,파폭명현승고,여지서반조비교차이유통계학의의(P<0.01).결론 첨몽효낭조적환자HAMD、ERPs P300、SSR、PSQI등지표균유명현개선,제시첨몽효낭비지서반능경위유효지연장환자적수면시간,개선수면질량.
Objective To observe the effect of Tianmeng capsule combined with deanxit and valium combined with deanxit on Hamilton Depressive Scale(HAMD),Auditory event-related potentials(ERPs),Sympathetic Skin Response(SSR)and Pittsburgh Sleep Quality Index(PSQI)in neuroses patients.Methods One hundred and twenty patients with neuroses were randomly divided into tianmeng capsule combined with deanxit group(Tianmeng capsule group)and valium combined with deanxit group(valium group)for 56 days.There were not significant differences between two groups in sexuality and age(P>0.05).The therapeutic effect was respectively evaluated by HAMD,ERPsP300,SSR,PSQI,before,1,2and 8 weeks after treatment.Results The total score of HAMD significantly decreased 1 week.2 weeks and 8 weeks after treatment in tianmeng capsule group(P<0.01).Meanwhite.the incubation period of SSR was significantly shortened and the amplitude significantly increased,showing a difference from valium group(P<0.01).Conclusions The study suggests that the effect of tianmeng capsule combined with deanxit on the neuroses patients iS superior to that of valium combined with deanxit.Tianmeng capsule combined with deanxit can improve the somnipathy and the function disorder of autonomic nerve in neuroses patients.
