合成化学
閤成化學
합성화학
CHINESE JOURNAL OF SYNTHETIC CHEMISTRY
2009年
6期
729-732
,共4页
朱万仁%李家贵%陈渊%黄肇宇%赵丽珍%孔新华
硃萬仁%李傢貴%陳淵%黃肇宇%趙麗珍%孔新華
주만인%리가귀%진연%황조우%조려진%공신화
2-乙酰噻吩%席夫碱%合成
2-乙酰噻吩%席伕堿%閤成
2-을선새분%석부감%합성
2-acetylthiophene%Schiff base%synthesis
以磷钨酸为催化剂,噻吩和乙酸酐反应合成了2-乙酰噻吩(1,收率83.5%);1与不同结构的酰肼反应合成了四种新型席夫碱(2a～2d),收率90%～95%,其结构经UV,~1H NMR,~(13)C NMR,IR及元素分析表征.优化了合成1和2的反应条件.
以燐鎢痠為催化劑,噻吩和乙痠酐反應閤成瞭2-乙酰噻吩(1,收率83.5%);1與不同結構的酰肼反應閤成瞭四種新型席伕堿(2a～2d),收率90%～95%,其結構經UV,~1H NMR,~(13)C NMR,IR及元素分析錶徵.優化瞭閤成1和2的反應條件.
이린오산위최화제,새분화을산항반응합성료2-을선새분(1,수솔83.5%);1여불동결구적선정반응합성료사충신형석부감(2a～2d),수솔90%～95%,기결구경UV,~1H NMR,~(13)C NMR,IR급원소분석표정.우화료합성1화2적반응조건.
2-Acetylthiophene(1) in yield 83.5% was prepared by the reaction of thiophene with acetic anhydride using phosphotungstic acid as the catalyst. Four new Schiff bases(2a～2d) in yields of 90%～95% were synthesized by the reaction of 1 with acylhydrazine. The structures were characterized by UV, ~1H NMR, ~(13)C NMR, IR and elemental analysis. The reaction condition of synthesizing 1 and 2 were optimized.
