CAJ | 학술논문

把具有良好抗凝血性能的卵磷脂-肝素(Pc-hep)复合物插层进入蒙脱土(MMT)中,制备出一系列新型的PC-hep/MMT纳米中间体.通过XRD对纳米中间体的结构和性能进行了表征;在此基础上,用复钙化时间曲线和溶血试验表征了纳米中间体的血液相容性,可以看出当随着材料的浓度增加,复钙时间曲线由陡峭趋于平滑;同时材料的溶血率都低于5%说明材料有很好的血液相容性,因此可以作为生物材料用于医用领域.
파구유량호항응혈성능적란린지-간소(Pc-hep)복합물삽층진입몽탈토(MMT)중,제비출일계렬신형적PC-hep/MMT납미중간체.통과XRD대납미중간체적결구화성능진행료표정;재차기출상,용복개화시간곡선화용혈시험표정료납미중간체적혈액상용성,가이간출당수착재료적농도증가,복개시간곡선유두초추우평활;동시재료적용혈솔도저우5%설명재료유흔호적혈액상용성,인차가이작위생물재료용우의용영역.
In the paper,a novel compound of phosphatidylcholine-heparin (PC-hep)with favorable anticoagulant was intercalated in montmorillonite (MMT). The structure and properties of the compound were characterized by X-ray diffraction(XRD). The blood compatibility of the composites were evaluated by curve of recalcification time and hemolysis test. The resurts show that recalcification time by the steep curve tends to smooth with the increase in the concentration of material. It was observed that hemolysis was less than 5 % in all the cases, which comes well within permissible limit. Hence,it may be conclude that the synthesized PC- hep/MMT nanocompos-ites may he suitable as biomaterials in the field of medical.