CAJ | 학술논문

目的：研究银杏叶制剂对老年性痴呆临床前期认知功能减退的防治作用。方法：采用Benton视觉保持测验进行治疗前后对比研究。结果：显示老年性痴呆临床前期人群中已存在认知功能减退，表现为正确分减少、错误分增多。错误以主图遗漏、变形、旋转和辅图的持续及遗漏为主，并与认知功能减退程度相关，服药三个月后，轻异组中正确分提高人数达60.98％与降分者比较具有非常显著差异(p＜0.001)，错误分下降例数达56％与增加者比较也具显著差异(p＜0.05)，达正常标准者由原来的7人增加至15人(p＜0.05)。结论：通过信度和效度良好的视觉保持测验，显示银杏制剂对老年性痴呆临床前期人群具有防治认知功能减退作用。
목적：연구은행협제제대노년성치태림상전기인지공능감퇴적방치작용。방법：채용Benton시각보지측험진행치료전후대비연구。결과：현시노년성치태림상전기인군중이존재인지공능감퇴，표현위정학분감소、착오분증다。착오이주도유루、변형、선전화보도적지속급유루위주，병여인지공능감퇴정도상관，복약삼개월후，경이조중정학분제고인수체60.98％여강분자비교구유비상현저차이(p＜0.001)，착오분하강례수체56％여증가자비교야구현저차이(p＜0.05)，체정상표준자유원래적7인증가지15인(p＜0.05)。결론：통과신도화효도량호적시각보지측험，현시은행제제대노년성치태림상전기인군구유방치인지공능감퇴작용。
Objective: To study the effect of Gingo biloba on cognition of patients at the early stage of Alzheimer disease. Method: 180 subjects were screened for Alzheimer disease. 45 patients (male 40, female 5) at the early stage of Alzheimer disease were assessed by Benton Visual Retention Test before and after treatment with gingo biloba. Result: Before treatment, patient group showed some defect in cognitive unction: lees correct score, more error. After treatment with gingo biloba for 3 months, 61% patients had correct score increased (p＜0.001), 56％ had ernor decreased (p＜0.05) . Conclusion: Gingo biloba can improve the cognitive function of patients at early stage of AD.