CAJ | 학술논문

目的　利用胫骨定量超声(QUS)对正常人群进行普查，并对骨质疏松症及相关因素进行分析，为早期诊断和预测骨折危险性提供参考。方法　用骨定量超声仪检测1 368例健康者右胫骨超声速度(SOS)，并分析停经时间、骨折史等因素对SOS值的影响。结果　男性SOS峰值在40～44年龄组，女性在35～39年龄组。男性60岁以上各年龄组SOS下降，70岁以上下降更明显(P＜0.01)。女性50岁以上SOS即下降(P ＜0.05)。40岁以前女性SOS值高于男性，50岁以后女性明显低于男性(P＜0.01)。随着停经时间延长，女性SOS下降，停经5年以内下降迅速(P＜0.01)，5年以后下降缓慢。围绝经期妇女中，停经组明显低于同年龄未绝经组(P＜0.01)。低于青年组均值2 .0 SD发生率13.37%，50岁以上为18.19%。结论　老年人胫骨SOS明显下降，老年女性下降更为明显。停经因素是导致骨质疏松的重要因素之一。减少2.0 SD为骨质疏松症的诊断标准较适合本地区情况。QUS对早期诊断骨质疏松和预测骨折危险性具有快捷无创伤等优点。
목적　이용경골정량초성(QUS)대정상인군진행보사，병대골질소송증급상관인 소진행분석，위조기진단화예측골절위험성제공삼고。방법　용골정량초 성의검측1 368례건강자우경골초성속도(SOS)，병분석정경시간、골절사등인소대SOS치적 영 향。결과　남성SOS봉치재40～44년령조，녀성재35～39년령조。남성60세 이상각년령조SOS하강，70세이상하강경명현(P＜0.01)。녀성50세이상SOS즉하강(P ＜0.05)。40세이전녀성SOS치고우남성，50세이후녀성명현저우남성(P＜0.01)。 수착정경시간연장，녀성SOS하강，정경5년이내하강신속(P＜0.01)，5년이후하강완 만。위절경기부녀중，정경조명현저우동년령미절경조(P＜0.01)。저우청년조균치2 .0 SD발생솔13.37%，50세이상위18.19%。결론　노년인경골SOS명현하강，노년녀성하강경위명현。정경인소시도치 골질소송적중요인소지일。감소2.0 SD위골질소송증적진단표준교괄합본지구정황。QUS대 조기진단골질소송화예측골절위험성구유쾌첩무창상등우점。
Objective To make early diagnosis of osteoporosis and predict fracture risk according to the bone mass measurements by quantitative u ltrasound in normal people. Methods Quantitative ultrasound in tibia was measured in 1368 hea lthy persons in Ma'anshan City,China. Results The age groups at pe a k speed of sound(SOS)were 40-44 years in males and 35-39 years in females.In m ales,the SOS declined significontly in the group over 70 of age (P＞0.01) w hil e it began to fall at the age of over 50 in females (P＞0.05),especially o ver 55 (P＞0.01).The SOS in females under 40 years was higher than in males of that age, but SOS in women over 50 years was lower than in men of that age. T he SOS reduced with increasing years since menopause.The reduction was rapid wit hin 5 years after menopause (P＞0.01) and slowed down in farther years afte r menopause. In the period of perimenopause,the SOS was lower in menopausal w omen than i n non-menopausals of the same age (P＞0.01).When the SOS was 2.0 SD lowe r than that of the same age group,prevalence rate of osteoporosis was 13.37%, a nd it was 18.19% when over age 50. Conclusion The tibia SOS in the old people slows down significantl y. Menopause is one of the important factors causing osteoporosis. A reduction o f SOS by 2SD is a criterion suitable for diagnosing osteoporosis in this region.