CAJ | 학술논문

目的：探讨血脂在脑梗塞发病中的作用。方法：检测128例急性脑梗塞患者血脂4项指标含量，并与对照组[摘要]目的：探讨血脂在脑梗塞发病中的作用。方法：检测128例急性脑梗塞患者血脂4项指标含量，并与对照组80例的检测结果进行比较。同时将无合并症脑梗塞患者分别与脑梗塞合并高血压、糖尿病、冠心病患者的血脂水平进行比较。TC，TG及HDL-C等用酶法测定。LDL-C由TC，TG，HDL-C的检测数据按Friedwald公式计算。结果：脑梗塞患者的TC，TG，LDL-C，TC/HDL-C明显高于对照组(P＜0.01)，而其HDL-C明显低于对照组(P＜0.01)。脑梗塞合并高血压、合并糖尿病患者的血脂水平高于无合并症脑梗塞患者，但脑梗塞合并冠心病患者的血脂水平与后者无明显差别。结论：TC，TG，LDL-C，TC/HDL-C的水平升高，HDL-C下降与脑梗塞密切相关，故调脂治疗是非常必要的。
목적：탐토혈지재뇌경새발병중적작용。방법：검측128례급성뇌경새환자혈지4항지표함량，병여대조조[적요]목적：탐토혈지재뇌경새발병중적작용。방법：검측128례급성뇌경새환자혈지4항지표함량，병여대조조80례적검측결과진행비교。동시장무합병증뇌경새환자분별여뇌경새합병고혈압、당뇨병、관심병환자적혈지수평진행비교。TC，TG급HDL-C등용매법측정。LDL-C유TC，TG，HDL-C적검측수거안Friedwald공식계산。결과：뇌경새환자적TC，TG，LDL-C，TC/HDL-C명현고우대조조(P＜0.01)，이기HDL-C명현저우대조조(P＜0.01)。뇌경새합병고혈압、합병당뇨병환자적혈지수평고우무합병증뇌경새환자，단뇌경새합병관심병환자적혈지수평여후자무명현차별。결론：TC，TG，LDL-C，TC/HDL-C적수평승고，HDL-C하강여뇌경새밀절상관，고조지치료시비상필요적。
Objective: To investigate the role of serum lipids in the pathogenesis of cerebral infaraction (CI) .Methods: The four indices of serum lipids in 128 patients with CI (patient group) and 80 healthy persons(control group) were measured and compared. The serum lipids of CI without complicated diseases patients were compared with that of CI complicated hypertension, CI complicated diabetes and CI complicated coronary heart diseases patients respectively. Methods: TC, TG and HDL-C were measured by enzyme method. According to Friedwald formular LDL-C could be calculated with measured data of TC, TG, HDL-C. Results:TC, TG, LDL-C and TC/HDL-C of CI patients were significantly higher than those of control group (P＜0.01) and their HDL-C was significantly lower than that of the latter(P ＜0.01). The serum lipid level of CI complicated hipertension and complicated diabetes patients was higher than that of CI without complicated diseases patients. But the serum lipid of CI complicated coronary heart disease patients had the same level as that of CI without complicated diseases patients. Conclusion: The results suggest that the higher levels of TC, TG, LDL-C,TC/HDL-c and lower level of HDL-C are intimately related to CI. Thus it is very necessary to regulate the lipid level in CI treatment.