CAJ | 학술논문

文冠木正丁醇提取物对二甲苯致小鼠耳肿胀、蛋清致大鼠足肿胀、角叉菜胶致小鼠足肿胀、醋酸致小鼠腹腔毛细血管通透性增加、小鼠羧甲基纤维素囊中白细胞游走、小鼠棉球肉芽肿生长均有显著的抑制作用，同样剂量下，文冠木正丁醇提取物对角叉菜胶致去双侧肾上腺小鼠足肿胀仍有显著的抑制作用，且对小鼠肾上腺重量及肾上腺中维生素C的含量没有明显影响。
문관목정정순제취물대이갑분치소서이종창、단청치대서족종창、각차채효치소서족종창、작산치소서복강모세혈관통투성증가、소서최갑기섬유소낭중백세포유주、소서면구육아종생장균유현저적억제작용，동양제량하，문관목정정순제취물대각차채효치거쌍측신상선소서족종창잉유현저적억제작용，차대소서신상선중량급신상선중유생소C적함량몰유명현영향。
The anti-inflammatory effect of n-butanol extract of Xanthocerassorbifolia Bunge(BEX)was studied in this paper.The ear edema resulted from dimethyl benzene,paw edema induced by carrageenin,the increase of vascular permeability caused by acetic acid,the chemotaxis of WBC induced by CMC and the weight of cotton granuloma in mice and hind paw edema induced by fresh egg white in rats were inhibited significantly by ig BEX daily for 7 days,respectively.The carrageenin-induced paw edema was also inhibited markedly in adrenal-ectomiced mice.No changes in weight of adrenal and the concentration of vitamin C were observed,indicating that the anti-inflammatory effect of BEX was not related to pituitary-adrenal system.