CAJ | 학술논문

目的:探讨肺癌手术患者应用针刺对γ-干扰素(INF-γ)和肿瘤坏死因子(TNF)的调节.方法:采用双抗体夹心免疫酶标法(ELISA)检测肺癌患者血清中INF-γ和肿瘤坏死因子含量;将针药麻组与全麻组肺癌手术患者各30例,分别在术前、术后8日、术后12日测量INF-γ和TNF含量作比较.结果:血清中INF-γ含量在术前作两组比较无明显差异(P＞0.05).术后第8日和第12日作两组比较均有显著差异(P＜0.05),针药麻组优于全麻组.自身比较针药麻组术后第12日和术后第8日比较有显著差异(P＜0.05).血清中肿瘤坏死因子含量在术前作两组比较(P＞0.05)无明显差异;在术后第8日及术后第12日作比较(P＜0.05)均有显著差异.结论: 肺癌手术患者应用针刺能升高血清中INF-γ和TNF含量,对肺癌手术患者有免疫调节功能.
목적:탐토폐암수술환자응용침자대γ-간우소(INF-γ)화종류배사인자(TNF)적조절.방법:채용쌍항체협심면역매표법(ELISA)검측폐암환자혈청중INF-γ화종류배사인자함량;장침약마조여전마조폐암수술환자각30례,분별재술전、술후8일、술후12일측량INF-γ화TNF함량작비교.결과:혈청중INF-γ함량재술전작량조비교무명현차이(P＞0.05).술후제8일화제12일작량조비교균유현저차이(P＜0.05),침약마조우우전마조.자신비교침약마조술후제12일화술후제8일비교유현저차이(P＜0.05).혈청중종류배사인자함량재술전작량조비교(P＞0.05)무명현차이;재술후제8일급술후제12일작비교(P＜0.05)균유현저차이.결론: 폐암수술환자응용침자능승고혈청중INF-γ화TNF함량,대폐암수술환자유면역조절공능.
Objective:To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases. Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immuno-enzymatic method (ELISA); to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups. Results:The pre-operation INF-γ contents of the two groups showed no significant difference (P＞0.05); the post-operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation (P＜0.05); the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation (P＜0.05); the pre-operation TNF contents of the two groups showed no significant difference (P＞0.05) and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation (P＜0.05). Conclusion:Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.