中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
9期
676-679
,共4页
LASEK%丝裂霉素C%Haze
LASEK%絲裂黴素C%Haze
LASEK%사렬매소C%Haze
Laser subepithelial keratomileusis%Mitomycin C%Haze
目的 探讨准分子激光上皮下角膜磨镶术(LASEK)术中联合应用丝裂霉素C(MMC)对术后角膜上皮下雾状浑浊(haze)的预防作用.方法 随机对60例(120眼)高度近视(-6.00D以上)左右眼分别做单纯LASEK手术和LASEK+ MMC手术,观察6个月,计算出haze反应的发生率并进行比较.结果 统计术后1、3、6个月haze的发生率,单纯LASEK分别为:0.5级,58.33％、48.33％、40.00％;1级,13.33％、8.33％、5.00％；2级,0、1.67％、1.67％；3级以上均为0.LASEK+MMC 分别为:0.5级,36.67％、26.67％、13.33％；1级,1.67％、1.67％、3.33％；2级以上均为0.两组比较差异有统计学意义(P＜0.05).结论 LASEK术中应用MMC能减轻haze反应形成,情况显著优于单纯LASEK手术.
目的 探討準分子激光上皮下角膜磨鑲術(LASEK)術中聯閤應用絲裂黴素C(MMC)對術後角膜上皮下霧狀渾濁(haze)的預防作用.方法 隨機對60例(120眼)高度近視(-6.00D以上)左右眼分彆做單純LASEK手術和LASEK+ MMC手術,觀察6箇月,計算齣haze反應的髮生率併進行比較.結果 統計術後1、3、6箇月haze的髮生率,單純LASEK分彆為:0.5級,58.33％、48.33％、40.00％;1級,13.33％、8.33％、5.00％；2級,0、1.67％、1.67％；3級以上均為0.LASEK+MMC 分彆為:0.5級,36.67％、26.67％、13.33％；1級,1.67％、1.67％、3.33％；2級以上均為0.兩組比較差異有統計學意義(P＜0.05).結論 LASEK術中應用MMC能減輕haze反應形成,情況顯著優于單純LASEK手術.
목적 탐토준분자격광상피하각막마양술(LASEK)술중연합응용사렬매소C(MMC)대술후각막상피하무상혼탁(haze)적예방작용.방법 수궤대60례(120안)고도근시(-6.00D이상)좌우안분별주단순LASEK수술화LASEK+ MMC수술,관찰6개월,계산출haze반응적발생솔병진행비교.결과 통계술후1、3、6개월haze적발생솔,단순LASEK분별위:0.5급,58.33％、48.33％、40.00％;1급,13.33％、8.33％、5.00％；2급,0、1.67％、1.67％；3급이상균위0.LASEK+MMC 분별위:0.5급,36.67％、26.67％、13.33％；1급,1.67％、1.67％、3.33％；2급이상균위0.량조비교차이유통계학의의(P＜0.05).결론 LASEK술중응용MMC능감경haze반응형성,정황현저우우단순LASEK수술.
Objective To observe the applying of mitomycin C in LASEK surgery to prevent the formation of subepithelial corneal haze in patients with high myopia.Methods Sixty patients ( 120 eyes) with high myopia were randomly performed LASEK on one eye,and they were performed 0.02％ mitomycin C treatment during LASEK on the other eye separately.Regular follow-up of 6 month was done to observe the haze formation.Results In the LASEK group,the rate of the haze of grade 0.5 was 58.33％,48.33％,40.00％ in 1 month,3 months and 6 months,that of grade 1 was 13.33％,8.33％,5.00％,that of grade 2 was 0,1.67％,1.67％,that of grade 3 and 4 was 0.In the LASEK + MMC group,the rate of the haze of grade 0.5 was 36.67％,26.67％,13.33％ in 1 mouths,3 months and 6 months respectively,that of grade 1 was 1.67％,1.67％,3.33％,that of grade 2,3 and 4 was 0.There was significant difference (P＜0.05) in the haze between the two groups.Conclusion The occurrence of the haze in the LASEK + MMCgroup is milder than that in the LASEK group.
