北京15个城区社区成人糖尿病人群伴发代谢综合征及其组分的特征分析:北京社区糖尿病研究2
북경15개성구사구성인당뇨병인군반발대사종합정급기조분적특정분석:북경사구당뇨병연구2
Clinical characteristics of diabetic patients with metabolic syndrome and its components at 15 urban communities in Beijing
  • 万方数据
    中华全科医师杂志 중화전과의사잡지
    CHINESE JOURNAL OF GENERAL PRACTITIONERS
    2011年 6期 390-393 ,共4页

    傅汉菁%袁申元%万钢%朱良湘%袁明霞%杨光燃%潘素芳%卜祥雷%张建东%杜雪平%李玉玲%季宇%谷晓宁%李月%崔学利%白薇%陈玉洁%王自明%朱庆生%高迎%柳德元%姬云涛%杨泽

    부한정%원신원%만강%주량상%원명하%양광연%반소방%복상뢰%장건동%두설평%리옥령%계우%곡효저%리월%최학리%백미%진옥길%왕자명%주경생%고영%류덕원%희운도%양택

    社区%糖尿病,2型%代谢综合征X 社區%糖尿病,2型%代謝綜閤徵X
    사구%당뇨병,2형%대사종합정X
    Community%Diabetes,type 2%Metabolic syndrome
    目的 了解北京城区社区糖尿病人群伴发代谢综合征及其组分的临床特征.方法 对2008年参加北京三甲医院与15个城区社区联合开展糖尿病纵向管理项目的 3295例2型糖尿病患者,按中华医学会代谢综合征诊断标准分为单纯糖尿病组、糖尿病伴1项代谢异常组、糖尿病伴2项代谢异常组及糖尿病伴3项代谢异常组,行糖尿病、代谢综合征的临床特征分析.结果 ①在本研究中,单纯糖尿病占4.7%(155/3295),95.3%(3140/3295)的患者有1项及以上其他的代谢异常,其中糖尿病伴1项代谢异常占32.6%(1075/3295),糖尿病伴2项代谢异常占42.1%(1386/3295),糖尿病伴3项代谢异常占20.6%(679/3295).糖尿病伴代谢综合征为62.7%(2065/3295).②糖尿病伴随代谢异常的组分越多,其体重指数(8MI)、腰围、腰臀比、收缩压、舒张压、空腹胰岛素水平、甘油三酯(TG)升高越显著,高密度脂蛋白胆固醇(HDL-C)下降越明显、胰岛素抵抗越严重(P<0.01).③随着代谢异常的组分增多,女性比例从单纯糖尿病组的49.0%(76/155)增加到糖尿病伴3项代谢异常组的61.9%(420/679)(P<0.01).④多元逐步回归分析显示,BMI、高血压史、HDL-C降低、高TG及血压控制不达标均是糖尿病合并代谢综合征的危险因素.结论 在北京城区社区糖尿病人群中,95.3%患者伴其他代谢异常,62.7%患者伴发代谢综合征.对糖尿病管理不能只控制血糖,必须进行血糖、血压、血脂、体重等的综合管理.
    목적 료해북경성구사구당뇨병인군반발대사종합정급기조분적림상특정.방법 대2008년삼가북경삼갑의원여15개성구사구연합개전당뇨병종향관리항목적 3295례2형당뇨병환자,안중화의학회대사종합정진단표준분위단순당뇨병조、당뇨병반1항대사이상조、당뇨병반2항대사이상조급당뇨병반3항대사이상조,행당뇨병、대사종합정적림상특정분석.결과 ①재본연구중,단순당뇨병점4.7%(155/3295),95.3%(3140/3295)적환자유1항급이상기타적대사이상,기중당뇨병반1항대사이상점32.6%(1075/3295),당뇨병반2항대사이상점42.1%(1386/3295),당뇨병반3항대사이상점20.6%(679/3295).당뇨병반대사종합정위62.7%(2065/3295).②당뇨병반수대사이상적조분월다,기체중지수(8MI)、요위、요둔비、수축압、서장압、공복이도소수평、감유삼지(TG)승고월현저,고밀도지단백담고순(HDL-C)하강월명현、이도소저항월엄중(P<0.01).③수착대사이상적조분증다,녀성비례종단순당뇨병조적49.0%(76/155)증가도당뇨병반3항대사이상조적61.9%(420/679)(P<0.01).④다원축보회귀분석현시,BMI、고혈압사、HDL-C강저、고TG급혈압공제불체표균시당뇨병합병대사종합정적위험인소.결론 재북경성구사구당뇨병인군중,95.3%환자반기타대사이상,62.7%환자반발대사종합정.대당뇨병관리불능지공제혈당,필수진행혈당、혈압、혈지、체중등적종합관리.
    Objective To study clinical characteristics of type 2 diabetic(T2D)patients with metabolic syndrome(MS)and its components in Beijing urban communities.Methods Totally,3295 T2D patients involved in a combined prospective diabetic management study from 15 urban communities in Beijing were classified as four groups, according to 2004 Chinese Diabetes Society's definition of MS, i. e, isolated T2D, T2D with one component of MS, T2D with two components of MS and T2D with three components of MS. Their clinical characteristics were analyzed. Results ( 1 ) Among 3295 T2D patients, 155 (4. 7% )were isolated T2D, 107 (32.6%) T2D with one component of MS, 1386 (42.1%) T2D with two components of MS and 679 (20.6%) T2D with three components of MS, with an overall 62.7% (2065/3295) of T2D patients complicated with MS. (2) In these T2D patients, the more components of MS they had, the higher body mass index (BMI), waist circumference, waist to hip circumference ratio (WHR),systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting serum levels of insulin and triglyceride (TG) and the lower level of high-density lipoprotein-cholesterol (HDL) were presented (P <0. 01 ). (3) Percentage of isolated T2D in women increased from 49. 0% (76/155) to 61.9% (420/679)of those with three components of MS ( P < 0 01 ), with increasing of components of MS. (4) Multiple logistic regression analysis showed that BMI, history of hypertension, decreased HDL, increased TG,increased blood pressure, all were risk factors for T2D patients complicated with MS. Conclusions Among T2D patients in urban communities of Beijing, 95.3% (3140/3295) of them complicated with one or more components of MS, and 61.9% (420/679) of them complicated with MS. So, community diabetic management must be implemented in an all-round way, including control of blood pressure, blood lipids,body weight and so on, in addition to control of blood sugar.
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