CAJ | 학술논문

目的探讨重症手足口病患儿的临床诊断及治疗体会.方法采用回顾性分析的方法对本院所收治的68例重症手足口病病例的相关信息进行分析.结果 68例重症手足口病大部分发生在2岁以下儿童;发热61例,白细胞升高50例,皮肤黏膜疹发病率100%;部分病例出现天门冬氨酸氨基转移酶(AST)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)和空腹血糖升高;部分病例可并发中枢神经系统损伤,导致神经源性肺水肿和循环衰竭.危重症病例治疗困难,病死率达2.94%(2/68).本组病例中, EV71阳性者23例,CoxA16阳性者2例,其他肠道病毒阳性者18例.结论重症手足口病发病人群大部分为2岁以下儿童.提高诊断警惕性和及时识别出重症病例的早期临床征象及早期干预性治疗是降低手足口病病死率的关键环节.
목적 탐토중증수족구병환인적림상진단급치료체회.방법 채용회고성분석적방법대본원소수치적68례중증수족구병병례적상관신식진행분석.결과 68례중증수족구병대부분발생재2세이하인동;발열61례,백세포승고50례,피부점막진발병솔100%;부분병례출현천문동안산안기전이매(AST)、기산격매(CK)、기산격매동공매(CK-MB)、유산탈경매(LDH)화공복혈당승고;부분병례가병발중추신경계통손상,도치신경원성폐수종화순배쇠갈.위중증병례치료곤난,병사솔체2.94%(2/68).본조병례중, EV71양성자23례,CoxA16양성자2례,기타장도병독양성자18례.결론 중증수족구병발병인군대부분위2세이하인동.제고진단경척성화급시식별출중증병례적조기림상정상급조기간예성치료시강저수족구병병사솔적관건배절.
Objective To explore the clinical diagnosis and experiences of treatment of severe patients with HFMD in order to understand HFMD better and accumulate more experience of preventing and treating this disease. Methods Clinical data and treatment of the 68 cases of severe HFMD were analyzed retrospectively. Results In 68 severe cases of HFMD, 58 cases happened children with 2 years lower, fever 61 cases and efflorescence 68 cases (100%). WBC increase in 50 cases rose. AST, CK, CK-MB, LDH and Glu inrease partial cases. Neurogenic pulmonary edema(NPE)and circulation failure could occur on the cases with CNS injure. In 68 cases, 23 cases were EV71-positive, 2 cases were CoxA16-positive, 18 cases were other enterovirus-positive. Treatment of critical cases was difficult, case-fatality rate was high as 2.94%.Conclusions Severe HFMD mostly happened to the children with 2 years lower. Improving diagnosis consciousness and early intervention therapy are critical in reducing the fatality.