中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
2010年
6期
409-412
,共4页
盛新华%高春芳%季锡清%魏东%郑国宝
盛新華%高春芳%季錫清%魏東%鄭國寶
성신화%고춘방%계석청%위동%정국보
结直肠肿瘤%肿瘤复发%肿瘤转移%预后
結直腸腫瘤%腫瘤複髮%腫瘤轉移%預後
결직장종류%종류복발%종류전이%예후
Colorectal neoplasms%Neoplasm recurrence%Neoplasm metastasis%Prognosis
目的 探讨肿瘤根治术后复发的结肠癌与直肠癌患者生物学行为及预后差异.方法 回顾性分析132例结直肠癌(结肠癌36例,直肠癌96例)根治术后复发患者的临床资料,对其中结肠癌与直肠癌患者的临床病理特征及预后进行比较分析.结果本组结肠癌与直肠癌复发者其原发肿瘤在大体类型、组织学类型、分化程度及淋巴结转移方面的差异有统计学意义(P<0.05).结肠癌组与直肠癌组中位复发时间分别为14.0个月和21.5个月(P=0.028);并分别有16例(44.4%)和65例(67.7%)多部位复发(P=0.014);两组复发后3年生存率分别为15.6%和24.8%(P=0.026);上述差异均有统计学意义.结论 结肠癌与直肠癌在肿瘤生物学行为上存在着一定差异,直肠癌复发患者预后优于结肠癌复发者.
目的 探討腫瘤根治術後複髮的結腸癌與直腸癌患者生物學行為及預後差異.方法 迴顧性分析132例結直腸癌(結腸癌36例,直腸癌96例)根治術後複髮患者的臨床資料,對其中結腸癌與直腸癌患者的臨床病理特徵及預後進行比較分析.結果本組結腸癌與直腸癌複髮者其原髮腫瘤在大體類型、組織學類型、分化程度及淋巴結轉移方麵的差異有統計學意義(P<0.05).結腸癌組與直腸癌組中位複髮時間分彆為14.0箇月和21.5箇月(P=0.028);併分彆有16例(44.4%)和65例(67.7%)多部位複髮(P=0.014);兩組複髮後3年生存率分彆為15.6%和24.8%(P=0.026);上述差異均有統計學意義.結論 結腸癌與直腸癌在腫瘤生物學行為上存在著一定差異,直腸癌複髮患者預後優于結腸癌複髮者.
목적 탐토종류근치술후복발적결장암여직장암환자생물학행위급예후차이.방법 회고성분석132례결직장암(결장암36례,직장암96례)근치술후복발환자적림상자료,대기중결장암여직장암환자적림상병리특정급예후진행비교분석.결과본조결장암여직장암복발자기원발종류재대체류형、조직학류형、분화정도급림파결전이방면적차이유통계학의의(P<0.05).결장암조여직장암조중위복발시간분별위14.0개월화21.5개월(P=0.028);병분별유16례(44.4%)화65례(67.7%)다부위복발(P=0.014);량조복발후3년생존솔분별위15.6%화24.8%(P=0.026);상술차이균유통계학의의.결론 결장암여직장암재종류생물학행위상존재착일정차이,직장암복발환자예후우우결장암복발자.
Objective To explore the difference in tumor biological behaviors and prognosis between recurrent colon cancer and recurrent rectal cancer after radical operation. Methods Complete clinical and follow-up data of 132 patients with colorectal cancer developed recurrence,including 36 colon cancers and 96 rectal caners, after curative resection were retrospectively analyzed and compared with respect of clinical pathological features and prognosis between colon and rectal cancer.Results Significant differences were found in primary tumor gross type, histological type, tumor differentiation and lymph node metastasis between colon and rectal cancer (P<0.05). Colon cancer recurred earlier than rectal cancer after radical surgery with the median time to recurrence being 14.0 months and 21.5 months, respectively (P=0.028). The difference in multiple sites recurrence was also found between colon (n=16,44.4%) and rectal cancer (n=65,67.7%)(P=0.014). The 3-year survival rate of recurrent rectal cancer was better than that of colon cancer (24.8% vs 15.6% ,P=0.026).Conclusion There are some differences in tumor biological behaviors between colon and rectal cancer,and the prognosis of rectal cancer with recurrence is better than that of colon cancer.