CAJ | 학술논문

目的观察特拉唑嗪联合前列癃闭通胶囊治疗慢性非细菌性前列腺炎(NBP)的疗效.方法 102例NBP患者随机分为治疗组54例和对照组48例,治疗组口服特拉唑嗪+前列癃闭通胶囊；对照组口服特拉唑嗪+左氧氟沙星.分别观察治疗前、治疗4周、8周后慢性前列腺炎症状指数评分(NIH-CPSI)、前列腺按摩液(EPS)常规检查及尿流率的变化.结果治疗4周后,两组NIH-CPS总评分、症状评分、生活质量评分、疼痛症状评分及排尿症状评分较治疗前均明显改善(t=14.80、16.20、6.15、8.67、10.00、16.47、14.62、8.79、10.77、10.86,均P＜0.01)；治疗8周后,对照组NIH-CPS评分较治疗4周时无明显改善(均P＞0.05),治疗组较治疗4周时有明显改善(t=2.76、2.71、2.75、2.72、2.73,均P＜0.01).治疗4周后,两组AFR、MFR较治疗前均增加(t=11.56、11.84、13.85、12.80,均P＜0.01)；但两组间差异均无统计学意义(均P＞0.05).结论特拉唑嗪联合前列癃闭通胶囊治疗NBP可减轻临床症状,提高生活质量.
목적 관찰특랍서진연합전렬륭폐통효낭치료만성비세균성전렬선염(NBP)적료효.방법 102례NBP환자수궤분위치료조54례화대조조48례,치료조구복특랍서진+전렬륭폐통효낭；대조조구복특랍서진+좌양불사성.분별관찰치료전、치료4주、8주후만성전렬선염증상지수평분(NIH-CPSI)、전렬선안마액(EPS)상규검사급뇨류솔적변화.결과 치료4주후,량조NIH-CPS총평분、증상평분、생활질량평분、동통증상평분급배뇨증상평분교치료전균명현개선(t=14.80、16.20、6.15、8.67、10.00、16.47、14.62、8.79、10.77、10.86,균P＜0.01)；치료8주후,대조조NIH-CPS평분교치료4주시무명현개선(균P＞0.05),치료조교치료4주시유명현개선(t=2.76、2.71、2.75、2.72、2.73,균P＜0.01).치료4주후,량조AFR、MFR교치료전균증가(t=11.56、11.84、13.85、12.80,균P＜0.01)；단량조간차이균무통계학의의(균P＞0.05).결론 특랍서진연합전렬륭폐통효낭치료NBP가감경림상증상,제고생활질량.
Objective To investigate the effect and mechanism of terazosin combined with Qianlielongbitong in the treatment of non-bacterial prostatitis.Methods One hundred and two patients with non-bacterial prostatitis were divided into two groups:one group was treated with terazosin 4 mg qn and Qianlielongbitong,while the other group was treated with terazosin and Levoofloxacin.We compared three indices of chronic prostatitis symptom index (NIH-CPSI),prostatic secretion examination(EPS) and urodynamic data in three different steps:before treatment,after 4-week treatment and after 8-week treatment.Results The NIH-CPSI of both groups was greatly improved after treatment( all P ＜0.01 ).Inside the treatment group,the NIH-C-PSI after 8-week treatment was better than that after 4- week treatment ( all P ＜ 0.01 ).However,in both groups,there was no significant difference between the index after 8-week treatment and the one after 4 week.EPS,AFR and MFR were greatly improved in both groups( all P ＜0.01 ).Conclusion Terazosin can relieve the clinical symptom,and improve the life quality.