CAJ | 학술논문

目的研究加强监护病房(intensive care unit,以下简称ICU)内阴沟肠杆菌感染的临床、药敏以及细菌学的特点.方法回顾性分析ICU中83例院内阴沟肠杆菌感染病例.结果高龄、低蛋白血症、侵人性操作、长期住院及使用广谱抗生素是阴沟肠杆菌感染主要的高危因素.阴沟肠杆菌具有多重耐药性,除了亚胺培南对其敏感性较高外,它对多种抗生素耐药率超过了50%.结论减少侵入性操作和广谱抗生素的长期使用,根据药敏结果选择抗生素,能减少阴沟肠杆菌感染的发生.
목적 연구가강감호병방(intensive care unit,이하간칭ICU)내음구장간균감염적림상、약민이급세균학적특점.방법 회고성분석ICU중83례원내음구장간균감염병례.결과 고령、저단백혈증、침인성조작、장기주원급사용엄보항생소시음구장간균감염주요적고위인소.음구장간균구유다중내약성,제료아알배남대기민감성교고외,타대다충항생소내약솔초과료50%.결론 감소침입성조작화엄보항생소적장기사용,근거약민결과선택항생소,능감소음구장간균감염적발생.
Objective To study the antimicrobial susceptiblity,clinical and bacteriological characteristics of enterobacter cloacae infection in ICU. Methods 83 cases of ICU infected with enterobacter cloacae were analyzed retrospectively. Results The elderly, hypoproteinemia,invasive operation,long-term hospitalization and the abuse of broad-spectrum antibiotics were the risk factors of infection with enterobacter cloacae. Besides highly sensitive to imipenem, the bacterium was resistant to most antibiotics, many of whose drug resistance ratio is over 50%. Conclusion The patients in ICU should be avoided the long-term abuse of broad-spectrum antibiotics and invasive operation.Bacterial culture and antibiotic susceptibility test should be carried out promptly. They could reduce the incidence of enterobacter cloacae infection.