CAJ | 학술논문

目的初步观察乙醇松解在角膜缘上皮移植治疗翼状胬肉中的临床效果.方法随机分组对比研究.将176例(192只眼)初发翼状胬肉随机分A、B两组:A组(87例90只眼)单纯翼状胬肉切除联合角膜缘上皮移植;B组(B组89例102只眼)乙醇松解胬肉切除联合角膜缘上皮移植.对比观察两组角膜创面上皮愈合时间及复发率.结果 A组角膜创面愈合时间平均(5.47±1.33)d;B组平均(3.69±1.38)d,两组差异有统计学意义(t=9.0208;P<0.01).术后随访18～30个月,平均(22.5±5.6)个月,术后6月A、B组均无复发;A组术后6～12月复发3只眼;12～18月复发3只眼;18～24月后复发1只眼,复发率7.87%.B组术后6～18个月无复发,18～24月后复发2只眼,复发率1.96%,差异有统计学意义(U=8.802;P<0.01).结论乙醇松解胬肉切除联合角膜缘上皮移植从复发基础和原因两方面抑制胬肉复发,值的临床推广应用.
목적 초보관찰을순송해재각막연상피이식치료익상노육중적림상효과.방법 수궤분조대비연구.장176례(192지안)초발익상노육수궤분A、B량조:A조(87례90지안)단순익상노육절제연합각막연상피이식;B조(B조89례102지안)을순송해노육절제연합각막연상피이식.대비관찰량조각막창면상피유합시간급복발솔.결과 A조각막창면유합시간평균(5.47±1.33)d;B조평균(3.69±1.38)d,량조차이유통계학의의(t=9.0208;P<0.01).술후수방18～30개월,평균(22.5±5.6)개월,술후6월A、B조균무복발;A조술후6～12월복발3지안;12～18월복발3지안;18～24월후복발1지안,복발솔7.87%.B조술후6～18개월무복발,18～24월후복발2지안,복발솔1.96%,차이유통계학의의(U=8.802;P<0.01).결론 을순송해노육절제연합각막연상피이식종복발기출화원인량방면억제노육복발,치적림상추엄응용.
Objective To observe clinical effect of alcohol lysis combined with corneal limbus epithelial transplantation in the treatment of primary pterygium.Mcthods The prospective randomized paired-eye trial was studied.The 176 patients (192 eyes) with primary pterygium were allocated to two groups: excision of pterygium with corneal limbus epithelial transplantation surgery (Group A, 87 cases of 90 eyes) and alcohol lysis combined with corneal limbus epithelial transplantation (Group B, 89 cases of 102 eyes).The average epithelial healing time of postoperative wound on cornea and recurrence rate between Group A and Group B were compared.Results The average epithelial healing time of postoperative was (5.47±1.33) days in Group A and (3.69±1.38) days in group B.The difference between two groups was significant (t=9.0208,P<0.001).Followed up periods of postoperative eyes ranged from 18-30 (22.5±5.6) months, 7 of 90 eyes (7.87%) in Group A and 2 of 102 eyes (1.96%) in Group B were recurred.The difference was significant (U=8.802, P<0.01).Conclusions Alcohol lysis combined with corneal limbus epithelial transplantation can reduce the recurfence from both basis and cause, and it is worth for clinical application.