CAJ | 학술논문

乳酸杆菌表面蛋白(SLP)有调控肠上皮细胞(IEC)生物学功能的作用,已得到大多数学者的肯定.通过近年的研究,我们对IEC的黏附和定植机制也取得了一定的成果.但目前关于SLP的研究仍存在分子量较大、生物效价有限、结构域尚不清楚、抗感染能力有待提高和作用机制尚不清楚等问题.以下就SLP的分离、鉴定及其与IEC作用后引起细胞内生物学反应等方面的研究现状作一综述.
유산간균표면단백(SLP)유조공장상피세포(IEC)생물학공능적작용,이득도대다수학자적긍정.통과근년적연구,아문대IEC적점부화정식궤제야취득료일정적성과.단목전관우SLP적연구잉존재분자량교대、생물효개유한、결구역상불청초、항감염능력유대제고화작용궤제상불청초등문제.이하취SLP적분리、감정급기여IEC작용후인기세포내생물학반응등방면적연구현상작일종술.
Lactobacillus can maintain the stability of microbiological environment in intestine and its surface layer protein controls the biological function of intestinal epithelia cells. The mechanism of adhering had been studied. In this article, we review the progress of surface layer protein in the study of the isolation, identification and the biological reaction with the intestinal epithelia cells .