CAJ | 학술논문

多胺物质是一种小分子脂肪族物质,它在体内广泛分布,具备多种生理、病理作用,参与肿瘤的发生、细胞的稳定性、细胞周期及细胞凋亡等调控过程.对多胺物质的研究由来已久,虽然多胺物质与心脏离子通道的关系密切,但是受关注的程度仍然不够.随着对多胺物质了解的加深以及研究技术的完善,多胺的研究进入了一个新的纪元.本文聚焦在多胺物质与心脏离子通道的关系.
다알물질시일충소분자지방족물질,타재체내엄범분포,구비다충생리、병리작용,삼여종류적발생、세포적은정성、세포주기급세포조망등조공과정.대다알물질적연구유래이구,수연다알물질여심장리자통도적관계밀절,단시수관주적정도잉연불구.수착대다알물질료해적가심이급연구기술적완선,다알적연구진입료일개신적기원.본문취초재다알물질여심장리자통도적관계.
Polyamines are a group of small molecule aliphatic substances, which are widely distributed. They have a variety of physiological and pathological roles, such as tumor genesis, cell stability, cell cycle and apoptosis, and so on. Studies have not paid much attention to the relationship between polyamines and ion channels although it may be helpful in understanding the phenomena of arrhythmia and some types of heart diseases. With improvements in techniques and understanding of the mechanism underling the metabolism of polyamine, research is entering a new era. In this article, we examine the relationship between polyamine and cardiac ion channels.