CAJ | 학술논문

[目的]探讨急性亚硝酸盐中毒合并肝功能异常的临床特点与短期预后情况.[方法]对在本院住院治疗的急性亚硝酸盐中毒合并肝功能异常患者28例观察其并发症和短期预后,并与肝功能正常患者32例进行比较.[结果]与对照组相比,观察组患者禁食时间、住院时间和死亡率均明显升高(P<0.05);电解质紊乱、感染、心律失常、消化道出血等并发症发生率明显升高(P<0.05);肝功能与患者预后呈正相关(P<0.05).[结论]急性亚硝酸盐中毒病情凶险,肝功能损害对患者病情有明显影响,临床医师需充分认识该病的临床特点并尽早诊治,以改善预后.
[목적]탐토급성아초산염중독합병간공능이상적림상특점여단기예후정황.[방법]대재본원주원치료적급성아초산염중독합병간공능이상환자28례관찰기병발증화단기예후,병여간공능정상환자32례진행비교.[결과]여대조조상비,관찰조환자금식시간、주원시간화사망솔균명현승고(P<0.05);전해질문란、감염、심률실상、소화도출혈등병발증발생솔명현승고(P<0.05);간공능여환자예후정정상관(P<0.05).[결론]급성아초산염중독병정흉험,간공능손해대환자병정유명현영향,림상의사수충분인식해병적림상특점병진조진치,이개선예후.
[Objective] To investigate the clinical characteristic and short-term prognosis of acute poisoning by nitrite complicated with liver dysfunction. [Methods] The data of 28 cases with acute poisoning by nitrite complicated and liver dysfunction in our hospital were analyzed and the short-term prognosis was followed up and compared with that of 32 cases without liver dysfunction. [Results] Compared with the control group, the fasting time, length of stay, mortality and the incidence rate of electrolyte disturbances, infection, arrhythmia and alimentary tract hemorrhage in observation group were all increased(P<0.05). Liver function in patients was positively correlated with the prognosis(P<0.05)[Conclusion] The acute poisoning by nitrite is dangerous. Liver dysfunction may aggravate pathogenetic condition, so the clinician should know the disease completely, diagnose it and cure it early to improve the prognosis.