时珍国医国药
時珍國醫國藥
시진국의국약
LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH
2009年
11期
2777-2778
,共2页
张又枝%杨文哲%吕中明%罗欣桐
張又枝%楊文哲%呂中明%囉訢桐
장우지%양문철%려중명%라흔동
二苯乙烯苷%血液流变学%血栓
二苯乙烯苷%血液流變學%血栓
이분을희감%혈액류변학%혈전
THSG%Hemorheology%Thrombus
目的 观察二苯乙烯苷对大鼠血栓形成及血液流变学的影响.方法 用动静脉旁路方法 建立大鼠体外血栓模型,用冰水冷刺激加肾上腺素应激法建立大鼠血栓模型,观察二苯乙烯苷静脉给药5,10,20 mg/kg对大鼠血栓和血液流变学影响.结果 二苯乙烯苷明显降低大鼠血液粘度,抑制血栓形成.结论 二苯乙烯苷可有效用于抗血栓,改善血液流变学指标.
目的 觀察二苯乙烯苷對大鼠血栓形成及血液流變學的影響.方法 用動靜脈徬路方法 建立大鼠體外血栓模型,用冰水冷刺激加腎上腺素應激法建立大鼠血栓模型,觀察二苯乙烯苷靜脈給藥5,10,20 mg/kg對大鼠血栓和血液流變學影響.結果 二苯乙烯苷明顯降低大鼠血液粘度,抑製血栓形成.結論 二苯乙烯苷可有效用于抗血栓,改善血液流變學指標.
목적 관찰이분을희감대대서혈전형성급혈액류변학적영향.방법 용동정맥방로방법 건립대서체외혈전모형,용빙수랭자격가신상선소응격법건립대서혈전모형,관찰이분을희감정맥급약5,10,20 mg/kg대대서혈전화혈액류변학영향.결과 이분을희감명현강저대서혈액점도,억제혈전형성.결론 이분을희감가유효용우항혈전,개선혈액류변학지표.
Objective To observe the effects of tetrahydroxystilbene -glucoside (THSG) on the formation of thrombus and hemo-rheology of acute blood stasis in rats. Methods The acute blood stasis model was made by immersing the rat intoice - water with hypodermic injection of adrenalin hydrochloride and then treated with THSG 5,10,20mg/kg. The parameters of hemorheology was measured. Results THSG could significantly reduce the viscosities of the whole blood and plasma; inhibit the formation of experimental thrombus in rats. Conclusion THSG has activity of anti - thrombosis. It can improve the hemorheological parameters in acute blood stasis rats.
