CAJ | 학술논문

目的:找寻喉真菌病的特征性临床表现.方法:回顾性分析6例喉曲菌病患者的临床诊治资料.结果:6例患者在服抗真菌药1周内声嘶缓解,白斑消失,1个月内症状完全消失.随访6个月~4年,至今仍未见复发.结论:声带弥漫性充血、肥厚、散在片状白斑是特征性的体征,病理是确诊喉曲菌病的主要手段.确诊后停用抗生素和激素,改用伊曲康唑口服2～4周即可治愈.
목적:조심후진균병적특정성림상표현.방법:회고성분석6례후곡균병환자적림상진치자료.결과:6례환자재복항진균약1주내성시완해,백반소실,1개월내증상완전소실.수방6개월~4년,지금잉미견복발.결론:성대미만성충혈、비후、산재편상백반시특정성적체정,병리시학진후곡균병적주요수단.학진후정용항생소화격소,개용이곡강서구복2～4주즉가치유.
Objective:To discuss the distinctive clinical manifestation of primary aspergillus laryngitis.Method:Six cases of primary aspergillus laryngitis in our department were reviewed,among which 3 cases were diabetes patients,and were laryngeal mucosal barrier impairment.2 cases were smoking, 2 cases were over use of voice and 1 case were gastro-pharyngeal reflux . Refractory hoarseness was the main clinical manifestation of all patients. The prophase treatment with antibiotics and glucocorticoid should breakdown the balance of flora and exacerbate the disease.Result:Stop using antibiotics and glucocorticoid and alter to oral administration of itraconazole in 2 to 4 weeks after final diagnosis can effectively cure the disease. No recurrence was found in 6 month to 4 years follow up.Conclusion:Diffuse hyperemia ,pachynsis and scattered lamellar leukasmus of vocal cord were the characteristic physical findings of primary aspergillus laryngitis.Pathology is the major means to get the final diagnosis. Oral administration of itraconazole could be effective.