国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2008年
4期
284-287
,共4页
张光明%徐峰波%史央%肖宝荣
張光明%徐峰波%史央%肖寶榮
장광명%서봉파%사앙%초보영
树突细胞%食管肿瘤%肿瘤疫苗%免疫疗法
樹突細胞%食管腫瘤%腫瘤疫苗%免疫療法
수돌세포%식관종류%종류역묘%면역요법
Dendritic cells%Esophageal neoplasms%Cancer vaccines%Immunotheropy
随着树突状细胞(DC)体外扩增技术和肿瘤抗原制备、负载体系等DC疫苗制备技术的发展,与食管癌治疗相关的多种DC疫苗相继出现,包括多肽负载DC疫苗、食管癌细胞-DC融合疫苗、核酸负载DC疫苗、自体肿瘤抗原负载DC疫苗等,其中多肽负载DC疫苗及凋亡的自体肿瘤细胞负载DC疫苗等在临床应用中已取得较好疗效.
隨著樹突狀細胞(DC)體外擴增技術和腫瘤抗原製備、負載體繫等DC疫苗製備技術的髮展,與食管癌治療相關的多種DC疫苗相繼齣現,包括多肽負載DC疫苗、食管癌細胞-DC融閤疫苗、覈痠負載DC疫苗、自體腫瘤抗原負載DC疫苗等,其中多肽負載DC疫苗及凋亡的自體腫瘤細胞負載DC疫苗等在臨床應用中已取得較好療效.
수착수돌상세포(DC)체외확증기술화종류항원제비、부재체계등DC역묘제비기술적발전,여식관암치료상관적다충DC역묘상계출현,포괄다태부재DC역묘、식관암세포-DC융합역묘、핵산부재DC역묘、자체종류항원부재DC역묘등,기중다태부재DC역묘급조망적자체종류세포부재DC역묘등재림상응용중이취득교호료효.
Now with the technical development of dendritic cells (DC) amplification in vitro and the tumor antigen preparation and loading system, DC vaccines of esophageal carcinomas have been reported on papers one after the other, including the fusion vaccines of DC and esophageal carcinoma cells, polypeptide loaded DC vaccines, nucleic acid loaded DC vaccines, apoptosis autologous tumor antigen loaded DC vaccines; a-mong them, polypeptide loaded DC vaccines and apoptosis autologous tumor cells loaded DC vaccines have good effects in the clinical application.