中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2012年
2期
164-167
,共4页
王燕玲%格鹏飞%马奇毅%曹永琴%李洪波%郑菁%史文权%孙玮
王燕玲%格鵬飛%馬奇毅%曹永琴%李洪波%鄭菁%史文權%孫瑋
왕연령%격붕비%마기의%조영금%리홍파%정정%사문권%손위
碘%婴幼儿%发育
碘%嬰幼兒%髮育
전%영유인%발육
Iodine%Infants%Development
目的 探讨婴幼儿脑发育关键期碘营养状况与生长发育的关系.方法 2006-2010年在甘肃省临夏回族自治州对所有乡镇的女性从孕期开始补充碘油至哺乳期结束,并对断乳的3岁内婴幼儿补充碘油,然后从8县(市)分别按照东、西、南、北、中随机抽取5个乡,每个乡随机抽取1个村,每个村随机抽取0～3岁婴幼儿、孕妇及乳母各20名(不足者从邻近村庄补足),逐年监测孕妇、乳母、婴幼儿尿碘.2010年测定部分婴幼儿智商(DQ)、身高、体重.并抽取干预前0～3岁婴幼儿作为对照.结果 碘油干预前(2006年)和后(2007-2010年)各测定1056及2989名婴幼儿尿碘.干预后婴幼儿尿碘中位数从107.3 μg/L上升为139.6～ 190.7 μg/L,尿碘低于50 μg/L的比例从23.9％下降为6.7％～12.9％,DQ值从92.8提高为104.3,身高发育正常及以上的比例从65.0％上升为82.1％,体重正常及以上的比例从59.3％上升至81.4％,DQ值、身高和体重与干预前相比差异均有统计学意义(P＜0.05).孕妇尿碘从89.3 μg/L上升为118.2～ 187.8μg/L,乳母尿碘从84.9 μg/L上升为135.2 ～ 187.5μg/L.结论 脑发育关键期碘营养不足会导致婴幼儿生长发育落后,通过口服碘油能改善碘缺乏造成的生长发育障碍.
目的 探討嬰幼兒腦髮育關鍵期碘營養狀況與生長髮育的關繫.方法 2006-2010年在甘肅省臨夏迴族自治州對所有鄉鎮的女性從孕期開始補充碘油至哺乳期結束,併對斷乳的3歲內嬰幼兒補充碘油,然後從8縣(市)分彆按照東、西、南、北、中隨機抽取5箇鄉,每箇鄉隨機抽取1箇村,每箇村隨機抽取0～3歲嬰幼兒、孕婦及乳母各20名(不足者從鄰近村莊補足),逐年鑑測孕婦、乳母、嬰幼兒尿碘.2010年測定部分嬰幼兒智商(DQ)、身高、體重.併抽取榦預前0～3歲嬰幼兒作為對照.結果 碘油榦預前(2006年)和後(2007-2010年)各測定1056及2989名嬰幼兒尿碘.榦預後嬰幼兒尿碘中位數從107.3 μg/L上升為139.6～ 190.7 μg/L,尿碘低于50 μg/L的比例從23.9％下降為6.7％～12.9％,DQ值從92.8提高為104.3,身高髮育正常及以上的比例從65.0％上升為82.1％,體重正常及以上的比例從59.3％上升至81.4％,DQ值、身高和體重與榦預前相比差異均有統計學意義(P＜0.05).孕婦尿碘從89.3 μg/L上升為118.2～ 187.8μg/L,乳母尿碘從84.9 μg/L上升為135.2 ～ 187.5μg/L.結論 腦髮育關鍵期碘營養不足會導緻嬰幼兒生長髮育落後,通過口服碘油能改善碘缺乏造成的生長髮育障礙.
목적 탐토영유인뇌발육관건기전영양상황여생장발육적관계.방법 2006-2010년재감숙성림하회족자치주대소유향진적녀성종잉기개시보충전유지포유기결속,병대단유적3세내영유인보충전유,연후종8현(시)분별안조동、서、남、북、중수궤추취5개향,매개향수궤추취1개촌,매개촌수궤추취0～3세영유인、잉부급유모각20명(불족자종린근촌장보족),축년감측잉부、유모、영유인뇨전.2010년측정부분영유인지상(DQ)、신고、체중.병추취간예전0～3세영유인작위대조.결과 전유간예전(2006년)화후(2007-2010년)각측정1056급2989명영유인뇨전.간예후영유인뇨전중위수종107.3 μg/L상승위139.6～ 190.7 μg/L,뇨전저우50 μg/L적비례종23.9％하강위6.7％～12.9％,DQ치종92.8제고위104.3,신고발육정상급이상적비례종65.0％상승위82.1％,체중정상급이상적비례종59.3％상승지81.4％,DQ치、신고화체중여간예전상비차이균유통계학의의(P＜0.05).잉부뇨전종89.3 μg/L상승위118.2～ 187.8μg/L,유모뇨전종84.9 μg/L상승위135.2 ～ 187.5μg/L.결론 뇌발육관건기전영양불족회도치영유인생장발육락후,통과구복전유능개선전결핍조성적생장발육장애.
Objective To investigate the relationship between iodine nutrition and growth/ development in infants at the key period of brain development.Methods All women from pregnancy to the end of lactation and the weaning infants within 3 years in the Linxia Hui Autonomous Prefecture (Linxia Prefecture) were added iodized oil in 2006-2010.In 2006,2010 one town was randomly selected from each of the five directions (east,south,west,north,central) of each county in Linxia Prefecture.One village was chosen from every town and 20 infants,20 pregnant women and 20 lactating women were randomly selected in each town.Urinary iodine (UI) of the infants,pregnant and lactating women were determined.DQ value,height and weight of part of infants were measured.According to the above sampling plan,UI of pregnant women,lactating women and infants had been monitored every year after intervention.0-3 infants were choosing to be control before intervention.Results UI of 1056 and 2989 0-3 infants were investigated before and after the iodine oil intervention.After the ‘iodine oil' intervention,the median UI of infants increased from 107.3 μg/L to 139.6-190.7 μg/L,the percentage of UI level that lower than 50 μg/L,decreased from 23.9％ to 6.7％-12.9％.DQ value increased from 92.8 to 104.3,the percentage of normal height and above increased from 65.0％ to 82.1％ and the percentage of the normal weight and above,increased from 59.3％ to 81.4％.The outcomes of DQ value,height and weight showed statistically significant differences,compared to the pre- intervention outcomes (P＜0.05).The median UI of pregnant and lactating women increased from 89.3 μg/L to 118.2-187.8 μg/L and from 84.9 μg/L to 135.2-187.5 μg/Lrespectively.Conclusion Infant' s growth and development were retarded when iodine deficiency existed at the key period of brain development.Intake of oral iodine oil at key period of brain development could provide adequate nutrition thus improve growth and development on infants.
