中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2008年
19期
18-20
,共3页
同型半胱氨酸%内皮素%一氧化氮%叶酸%维生素B12%急性脑梗死
同型半胱氨痠%內皮素%一氧化氮%葉痠%維生素B12%急性腦梗死
동형반광안산%내피소%일양화담%협산%유생소B12%급성뇌경사
Homocysteine%Endothelin%Mononitrogen monoxide%Folic acid%VitamineB12%Cerebral infarction
目的 探讨血浆同型半胱氨酸(Hey)、内皮素(ET)、一氧化氮(NO)、叶酸(FA)、维生素B12(VitB12)水平变化与急性脑梗死(ACI)的关系.方法 测定110例ACI患者及51例健康对照者的血浆Hey、ET、NO、FA、VitB12含量.结果 ACI组血浆Hey[(17±5)μmol/L]、ET[(33±19)μmol/L]显著高于对照组[(10±3)μmol/L、(20±13)wnol/L],P<0.01;NO[(40±7)μmol/L]、FA[(8±4)ng/ml]、VitB12[(247±119)pg/ml]的水平低于对照组[(60±6)μmoL/L、(10±4)ng/ml、(412±194)pg/ml],P<0.01.结论 本研究对于患者病情观察、预后判断具有重要意义,尤其是在患者中推行加服FA和VitB12等制剂,为ACI的预防和治疗开辟了新的途径.
目的 探討血漿同型半胱氨痠(Hey)、內皮素(ET)、一氧化氮(NO)、葉痠(FA)、維生素B12(VitB12)水平變化與急性腦梗死(ACI)的關繫.方法 測定110例ACI患者及51例健康對照者的血漿Hey、ET、NO、FA、VitB12含量.結果 ACI組血漿Hey[(17±5)μmol/L]、ET[(33±19)μmol/L]顯著高于對照組[(10±3)μmol/L、(20±13)wnol/L],P<0.01;NO[(40±7)μmol/L]、FA[(8±4)ng/ml]、VitB12[(247±119)pg/ml]的水平低于對照組[(60±6)μmoL/L、(10±4)ng/ml、(412±194)pg/ml],P<0.01.結論 本研究對于患者病情觀察、預後判斷具有重要意義,尤其是在患者中推行加服FA和VitB12等製劑,為ACI的預防和治療開闢瞭新的途徑.
목적 탐토혈장동형반광안산(Hey)、내피소(ET)、일양화담(NO)、협산(FA)、유생소B12(VitB12)수평변화여급성뇌경사(ACI)적관계.방법 측정110례ACI환자급51례건강대조자적혈장Hey、ET、NO、FA、VitB12함량.결과 ACI조혈장Hey[(17±5)μmol/L]、ET[(33±19)μmol/L]현저고우대조조[(10±3)μmol/L、(20±13)wnol/L],P<0.01;NO[(40±7)μmol/L]、FA[(8±4)ng/ml]、VitB12[(247±119)pg/ml]적수평저우대조조[(60±6)μmoL/L、(10±4)ng/ml、(412±194)pg/ml],P<0.01.결론 본연구대우환자병정관찰、예후판단구유중요의의,우기시재환자중추행가복FA화VitB12등제제,위ACI적예방화치료개벽료신적도경.
Objective To investigate the changes of plasm levels of homocysteincand (Hey),endothelin(ET),mononitrogen monoxide(NO), folio acid (FA) and vitamine B12 (VitB12) in acute cerebral infarction patients. Methods Series of items of Hcy,ET, NO,FA and VitB12 from 110 cerebral infarction patients and 51 healthy individuals were deteete by DS30Hcy made by DREW and immulite impatus. Results The Hcy [(17±5)μmol/L] and ET[(33±19)μmol/L] values were increased in cerebral infarction group compared with that in control group [(10±3)μmol/L, (20±13)μmol/L respectively], and the difference were significant(P <0. 01). While values of NO[(40±7)μmol/L,FA[(8±4)ng/ml] and VitB12 [(247±119) pg/ml] were decreased compared with control group [(60±6)μmol/L,(10±4)ng/ml,(412±194) ng/ml respectively in correspondence],and the difference were significant (P < 0.01). Conclusion The surveillance of plasma Hcy, ET, NO, FA and VitB12 values are essential to the observation of the state of illness and prognosis,especially the gnidenee of clinical medication of prescription of FA and VitB12 to acute cerebral infarction patients.
