CAJ | 학술논문

目的分析复杂型睡眠呼吸暂停综合征(complex sleep apnea syndrome,CompSAS)患者临床特点.方法收集我院12例CompSAS患者作回顾性分析,比较经鼻持续气道正压通气(continuous positive airway pressure,CPAP)治疗前后睡眠质量、呼吸紊乱、压力变化情况.结果 12例CompSAS患者均为男性,体质量超重.CPAP压力滴定前经PSG检查诊断为以阻塞性呼吸暂停(OSA)、低通气为主的SAS,部分合并有中枢性呼吸暂停(CSA)、混合型呼吸暂停(MSA).在CPAP压力滴定时OSA、低通气、MSA得以消除,但CSA显著增多,与治疗前比较有显著差异,但治疗后AHI仍有显著降低(P＜0.001).但患者睡眠质量有所改善,平均S1+S2时间减少,REM时间增多,与治疗前有显著差异;缺氧总时间、最低氧饱和度均显著改善(P＜0.001).临床上无法给出一个合适的治疗压力.患者自觉症状部分改善.结论 CompSAS无法确定合适的CPAP治疗压力,但CPAP呼吸机能部分改善患者睡眠质量和氧合.
목적 분석복잡형수면호흡잠정종합정(complex sleep apnea syndrome,CompSAS)환자림상특점.방법 수집아원12례CompSAS환자작회고성분석,비교경비지속기도정압통기(continuous positive airway pressure,CPAP)치료전후수면질량、호흡문란、압력변화정황.결과 12례CompSAS환자균위남성,체질량초중.CPAP압력적정전경PSG검사진단위이조새성호흡잠정(OSA)、저통기위주적SAS,부분합병유중추성호흡잠정(CSA)、혼합형호흡잠정(MSA).재CPAP압력적정시OSA、저통기、MSA득이소제,단CSA현저증다,여치료전비교유현저차이,단치료후AHI잉유현저강저(P＜0.001).단환자수면질량유소개선,평균S1+S2시간감소,REM시간증다,여치료전유현저차이;결양총시간、최저양포화도균현저개선(P＜0.001).림상상무법급출일개합괄적치료압력.환자자각증상부분개선.결론 CompSAS무법학정합괄적CPAP치료압력,단CPAP호흡궤능부분개선환자수면질량화양합.
Objective A retrospective study of 12 complex sleep apnea syndrome (CompSAS)patients. Methods 12 CompSAS patients diagnosed in our hospital were collected and a comparison of sleep quality, respiratory events, saturation were made before and after Auto-CPAP titration. Results 12 CompSAS patients were all male and overweighed. All were diagnosed sleep apnea syndrome with dominantly OSA and hypopnea. OSA, hypopnea and mixed apnea were all eliminatied but CSA emerged significantily on Auto-CPAP titration night. Oxygen saturation developed significantly and sleep quality improved in spite of CSA existing. But suitable therapeutic pressure could not be achieved. Conclusions Although a suitable therapeutic pressure could not be achieved for CompSAS patients but Auto-CPAP improved sleep quality and oxygen saturation somehow.